Graduate Student Seminar Series – Sania Aftab

Graduate Student Seminar Series
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Location: 2nd Floor Auditorium (TRI/KITE) – 550 University Ave
Presentation Title: Developing novel methods to assess respiratory signals in asthma-OSA overlap
Abstract: Obstructive sleep apnea (OSA) and asthma are highly prevalent respiratory disorders that frequently coexist and worsen one another, partly due to airway narrowing and changes in intrathoracic pressure during sleep. Negative intrathoracic pressure generated during obstructive events may promote thoracic fluid shifts and small airway narrowing, contributing to increased airway resistance and reduced lung reactance. This research investigates respiratory asynchrony between chest and abdominal motion as a noninvasive surrogate marker of negative intrathoracic pressure and examines its relationship with overnight changes in thoracic fluid volume and airway mechanics. In parallel, this work evaluates the feasibility of textile-based wearable sensors for accurately and comfortably monitoring respiratory biomarkers, with the long-term goal of developing a clinically applicable, noninvasive system for assessing respiratory dysfunction in individuals with asthma and sleep apnea.
Supervisor Name: Azadeh Yadollahi
Year of Study: 2
Program of Study: MASc
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