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BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230713T140000
DTEND;TZID=America/Toronto:20230713T150000
DTSTAMP:20230705T202752Z
CREATED:20230705T202752Z
LAST-MODIFIED:20230705T202752Z
UID:10000227-1689256800-1689260400@bme.utoronto.ca
SUMMARY:Carbon nanomaterials for cardiac regenerative medicine
DESCRIPTION:Dr. Sanjiv Dhingra\, PhD\nUniversity of Manitoba\nAbstract: Donor derived allogeneic stem cells including mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) are being tested in animal studies and clinical trials for cardiac regeneration and repair. The outcome of initial studies was very encouraging and transplanted cells were safe in the recipient heart. However\, poor survival of transplanted stem cells in the infarcted heart has impaired the clinical translation of stem cells-based therapies. We have performed investigations to understand the mechanisms of poor survival of implanted stem cells in the heart. We found that allogeneic stem cells after transplantation in the ischemic heart turned immunogenic and were subsequently rejected by host immune system. In our ongoing studies we are focusing on understanding the mechanisms of increase in immunogenicity of allogeneic stem cells. We are also developing biomaterials-based strategies to prevent rejection of transplanted cells in the heart. We synthesized and characterized MXene quantum dots (MQDs). MQDs possess intrinsic immunomodulatory properties and selectively reduce activation of CD4+IFN-γ+ T-lymphocytes and promote expansion of immunosuppressive CD4+CD25+FoxP3+ regulatory T-cells in an activated lymphocyte population. We also incorporated MQDs into a chitosan-based hydrogel to create a 3D platform for stem cell delivery to the heart. This composite immunomodulatory hydrogel-based platform improved survival of stem cells and mitigated allo-immune responses. We also found that MQDs have potential to mitigate allograft vasculopathy and prevent rejection of transplanted organs. These studies highlight the potential of MXene based next generation biomaterials for cardiac regenerative medicine. \nAbout the speaker: Dr. Sanjiv Dhingra is a Professor at the University of Manitoba\,  Director of Canada Italy Tissue Engineering Program Institute of Cardiovascular Sciences and a researcher at St. Boniface Hospital Research Regenerative Medicine Program. He is a Professor at the Department of Physiology and Pathophysiology\, Biomedical Engineering Program Max Rady College of Medicine\, Rady Faculty of Health Sciences University of Manitoba.
URL:https://bme.utoronto.ca/event/carbon-nanomaterials-for-cardiac-regenerative-medicine/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:External Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230711T100000
DTEND;TZID=America/Toronto:20230711T110000
DTSTAMP:20230705T135639Z
CREATED:20230705T135506Z
LAST-MODIFIED:20230705T135639Z
UID:10000226-1689069600-1689073200@bme.utoronto.ca
SUMMARY:Polymer Nanoparticle Design and Delivery Strategies to Resolve Vascular Inflammation
DESCRIPTION:Dr. Laura Bracaglia\, PhD Villanova University\nPolymer nanoparticles (NPs) can provide a safe and efficient delivery mechanism for therapy directly at specific tissues and cells\, but achieving sufficient levels of NPs and therefore therapeutics in target tissues in humans has remained a barrier to the translation of this technology. The in vivo efficacy of polymeric NPs is dependent on their pharmacokinetics\, including time in circulation and resulting tissue tropism\, as well as intracellular trafficking and behavior. In this work\, we examine tunable chemical and molecular characteristics of polymer NPs to tailor the design for an intended therapeutic delivery – both to and within the target cell. We are particularly interested in designing NPs and delivery strategies which can direct therapeutics to endothelial cells to correct dysfunctional inflammation in the vasculature. I will present several approaches for nucleic acid and small molecule delivery using polymeric NPs in vitro\, in vivo\, and in ex vivo models of human tissue\, and show the impact of design changes on reducing inflammatory signaling. Our goal is to optimize NP design to combat dysfunctional inflammation locally and with more impact than globally administered therapies. \nBiography \nDr. Bracaglia joined the faculty at Villanova University in the fall of 2022 as an Assistant Professor in the Department of Chemical and Biological Engineering. She is continuing her research into NP-based therapeutic delivery to human vasculature and integrating these strategies with tissue-engineering to create tools for long-term immune \nmodulation. Specifically\, materials that provide support for tissue regrowth while temporarily inhibiting inflammation-related injury\, thus reducing the burden of chronic inflammation. This work was born out of work that Dr. Bracaglia conducted as a Postdoctoral Fellow in Biomedical Engineering at Yale University as part of Dr. W. Mark Saltzman’s research group\, as well as her graduate work\, where she developed vascular\, tissue engineered constructs using a combination of biological and synthetic materials at the University of Maryland with Dr. John Fisher in Bioengineering. \n\nHosted by Dr. Molly Shoichet Snacks and refreshments will be served
URL:https://bme.utoronto.ca/event/polymer-nanoparticle-design-and-delivery-strategies-to-resolve-vascular-inflammation/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:External Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230620T120000
DTEND;TZID=America/Toronto:20230620T130000
DTSTAMP:20230615T195953Z
CREATED:20230615T195640Z
LAST-MODIFIED:20230615T195953Z
UID:10000225-1687262400-1687266000@bme.utoronto.ca
SUMMARY:Enlightening Panel discussion: Navigating the Path to a Professorship Position
DESCRIPTION:Time: June 20th\, 12-1PM \nLocation: KITE\, UC Lecture theatre (basement) \n  \nAre you concerned how to secure a job in academia\, post-COVID? \nWe have four outstanding panelists who will start their career as Assistant Professors this fall. Please join us at a vibrant event\, co-sponsored by IEEE-EMBS Toronto and FIBRE\, to hear from our panelist and ask your questions. \nAnd\, there will be pizza too ? \nTo facilitate logistics of the event\, please kindly register at:   https://events.vtools.ieee.org/m/363572 \nIf you have any questions\, please feel free to reach out to Ivana Culjak at Ivana.Culjak@uhn.ca
URL:https://bme.utoronto.ca/event/enlightening-panel-discussion-navigating-the-path-to-a-professorship-position/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230620T110000
DTEND;TZID=America/Toronto:20230620T120000
DTSTAMP:20230607T141938Z
CREATED:20230607T141938Z
LAST-MODIFIED:20230607T141938Z
UID:10000224-1687258800-1687262400@bme.utoronto.ca
SUMMARY:The Journey from Concept to Commercial
DESCRIPTION:  \nPlease join us for an ECHO webinar featuring Garrett Schwab\, who will provide an overview of his vast experience developing and commercializing novel therapeutic medical technologies. \nXII Medical is a privately held medical technology company developing a novel neurostimulation system designed to improve patient experience and outcomes for the millions suffering from Obstructive Sleep Apnea. \nGuest Speaker\nGarrett Schwab\, BA\, MBA \nPresident and CEO\, XII Medical \nRegister in advance for this webinar. After registering\, you will receive a confirmation email containing information about joining the webinar.\nECHO is an entrepreneurship training program\, funded and organized in a partnership between (i) the Translational Biology and Engineering Program (TBEP)\, the University of Toronto component of the Ted Rogers Centre for Heart Research\, and (ii) the Health Innovation Hub (H2i). For more information\, visit: https://tedrogersresearch.ca/echo/
URL:https://bme.utoronto.ca/event/the-journey-from-concept-to-commercial/
CATEGORIES:Events & Workshops
ORGANIZER;CN="Translational Biology and Engineering Program (TBEP)":MAILTO:reception.tbep@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230609T140000
DTEND;TZID=America/Toronto:20230609T150000
DTSTAMP:20230509T151030Z
CREATED:20230509T151030Z
LAST-MODIFIED:20230509T151030Z
UID:10000220-1686319200-1686322800@bme.utoronto.ca
SUMMARY:Plasmon-enhanced Fluorescence Induced Stimulated Raman Scattering as Non-destructive Non-linear Optical Method in Nanobiosensing and Bioimaging
DESCRIPTION:Mohammad E. Khosroshahi\nNanobiophotonics & Biomedical Research Laboratory\, MIS-Electronics Inc.\, \nRichmond Hill\, Canada \n  \nAbstract \nThis work describes the generation and observation of multi-wavelengths due to stimulated Raman scattering (SRS) from deep red to near-infrared (NIR) induced by plasmon-enhanced fluorescence (PEF) of fluorescein isothiocyanate (FITC) conjugated gold nanoparticles (F-AuNP). The plasmonic solution was excited by a 488 nm diode laser and the PEF due to overlapping of FITC\, and localized surface plasmon resonance (LSPR) of AuNP resonance peaks provided an efficient coupling between the near-field of LSPR of AuNPs as a nano-antenna and the molecules followed by an enhanced emission. Resonance Rayleigh scattering and PEF conditions are both satisfied. PEF acts as Stokes radiation and secondary pump beam for further optical excitation within the medium. Longer wavelengths with higher output power and shorter wavelengths with lower are detected at varying angles. Time-resolved PEF spectroscopy revealed the effect of enhanced emission followed by its quenching. In addition\, F-AuNPs were incubated and taken up by the king oyster mushroom (KOM) grown in the lab studied by phase contrast microscope (PCM) and fluorescence microscope (FM). The results showed PEF and SRS visible colors within the mycelium hyphae. Therefore\, it is concluded that non-linear optical mechanisms can be utilized for non-destructive biomedical applications such as invitro and in vivo contrast-enhanced fluorescence sensing and nano-bioimaging of cells and tissues as monitoring techniques. \nBiography \nProfessor Mohammad E. Khosroshahi received his Ph.D. in Applied Physics (Application of Lasers in Medicine) from Hull University (UK) in 1993 with the thesis on ophthalmological tissue ablation with tunable mid-IR and excimer lasers in collaboration with Moorefields hospital in London. He joined the Biomaterial and Tissue Engineering group of the Faculty of Biomedical Engineering at Amirkabir University of Technology (AUT) in Tehran where he was a Full Professor. He has been the Director of AUT Laser and Optics Research Center\, Associate Dean of Research\, and Chair of Biomaterial Group. In 2013\, he joined the University of Toronto\, Department of Mechanical & Industrial Engineering (MIE) as a Visiting Professor working on ‘’Contrast-enhanced photoacoustic imaging of Tumor’’ at the Center for Advanced Diffusion-Wave and Photoacoustic Technologies (CADIPT). He then continued as a research associate at CADIPT working on the contrast-enhanced imaging of blood and became the faculty adjunct Professor in 2018. \nProfessor Khosroshahi is the author of two books:  Laser Applications in Medicine\, and Applications of Biophotonics and Nanobiomaterials in Biomedical Engineering\, and co-author of two book chapters on Laser surface modification of titanium alloys as biomedical implants. He has published 110 peer-reviewed papers and has 2 patents and patent-pending related to nanobiosensors. His main research interests are Nanobiophotonics\, Nanomedicine\, Multifunction nanostructures\, Targeted drug delivery\, Targeted photothermal therapy\, Guided bioimaging\, biological chaos\, Cancer thermodynamics\, Optical detection of dental decay\, Photoacoustic and Photothermal characterization. Currently\, Professor Khosroshahi is Director of the Nanobiophotonics and Biomedical Research Lab at MIS-Electronics in Richmond Hill where he is working on the development of novel colloidal and substrate nanobiosensors based on the Plasmon-enhanced fluorescence spectroscopy (PEFS) and Enhanced-surface-enhanced Raman scattering (E-SERS) for targeted detection of breast cancer biomarkers such as HER-II and CA 15-3\, dual-mode guided bioimaging\, fluorescence microscopy\, and contrast phase microscopy. He is a member of the Editorial Board of the Journal of Nanomedicine and Nanotechnology\, a fellow member of the Institute of Nanotechnology\, a member of the Canadian Association of Physics\, Canadian Medical and Biological Engineering Society\, Optical Society of America\, and SPIE.
URL:https://bme.utoronto.ca/event/plasmon-enhanced-fluorescence-induced-stimulated-raman-scattering-as-non-destructive-non-linear-optical-method-in-nanobiosensing-and-bioimaging/
LOCATION:MC 331\, 5 King's College Rd\, Toronto\, ON\, M5S 3G8\, Canada
CATEGORIES:External Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230530T110000
DTEND;TZID=America/Toronto:20230530T120000
DTSTAMP:20230504T155027Z
CREATED:20230504T155027Z
LAST-MODIFIED:20230504T155027Z
UID:10000219-1685444400-1685448000@bme.utoronto.ca
SUMMARY:Start-up Lessons: Concept to Commercialization of a Wearable Medical Monitoring Solution for Acute Care Patients
DESCRIPTION:  \nPlease join us for an ECHO webinar featuring Dr. Devin McCombie\, who will provide an overview of his vast experience commercializing wearable medical monitoring solutions at Sotera and Dexcom. \nDexcom Inc. develops\, manufactures\, produces\, and distributes continuous glucose monitoring systems for diabetes management. Sotera Inc. is a digital health start-up company that commercialized and sold a first-of-its-kind wearable vital sign monitoring solution to detect deterioration of acute care patients on the hospital general ward. \n  \nGuest Speaker \nDr. Devin McCombie\, PhD \nPast CEO\, Sotera Digital Health \nPresident\, Theorem Medtech LLC \nPrincipal Tech Lead\, Dexcom Inc. \n  \nRegister in advance for this webinar. After registering\, you will receive a confirmation email containing information about joining the webinar. \nECHO is an entrepreneurship training program\, funded and organized in a partnership between (i) the Translational Biology and Engineering Program (TBEP)\, the University of Toronto component of the Ted Rogers Centre for Heart Research\, and (ii) the Health Innovation Hub (H2i). For more information\, visit: https://tedrogersresearch.ca/echo/
URL:https://bme.utoronto.ca/event/start-up-lessons-concept-to-commercialization-of-a-wearable-medical-monitoring-solution-for-acute-care-patients/
CATEGORIES:Events & Workshops
ORGANIZER;CN="Translational Biology and Engineering Program (TBEP)":MAILTO:reception.tbep@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230519T130000
DTEND;TZID=America/Toronto:20230519T140000
DTSTAMP:20230509T183039Z
CREATED:20230509T183039Z
LAST-MODIFIED:20230509T183039Z
UID:10000221-1684501200-1684504800@bme.utoronto.ca
SUMMARY:BME Faculty Search Seminar - Nova Pishesha
DESCRIPTION:Exploiting Antigen Presentation Pathways for Precision Immune Engineering \nDr. Nova Pishesha\,\nJunior Fellow\, Society of Fellows at Harvard University\nCurrent treatments for autoimmunity rely on general immunosuppression\, which exposes patients to opportunistic infections. Hence\, immunoregulatory modalities\, which educate the immune system to induce antigen-specific tolerance are desirable. My doctoral research revolved around engineered red blood cells (RBCs) to treat preclinical models of autoimmune diseases by hijacking the tolerogenic RBC clearance pathways. As a postdoctoral fellow\, I worked on an alpaca-derived single domain antibody fragment (nanobody)-based platform. I have engineered these nanobodies to efficiently target antigen presenting cells and transmit either tolerogenic or vaccinal signal to antigen-specific immune cells. I showed that a single dose of a VHH that recognizes major histocompatibility complex class II/MHCII (VHHMHCII)\, conjugated to a myelin peptide and an anti-inflammatory corticosteroid\, i.e. dexamethasone (VHHMHCII-MOG-DEX)\, affords lasting protection in a mouse model of multiple sclerosis (MS). A single dose of VHHMHCII-MOG-DEX also reverses paralyses in mice without compromising the capacity of the immune system to fight pathogens. I further developed this technology for treating type 1 diabetes and as a SARS-CoV-2 vaccine. My independent group will aspire to produce novel treatments for autoimmune and infectious diseases. \nTalk will be in-person and virtual\, see information below.
URL:https://bme.utoronto.ca/event/bme-faculty-search-seminar-nova-pishesha/
LOCATION:MS3153
CATEGORIES:BME Faculty Search
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/05/1517545306211.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230518T180000
DTEND;TZID=America/Toronto:20230518T190000
DTSTAMP:20230425T141531Z
CREATED:20230425T141510Z
LAST-MODIFIED:20230425T141531Z
UID:10000218-1684432800-1684436400@bme.utoronto.ca
SUMMARY:Operability of the heart lung machine
DESCRIPTION:
URL:https://bme.utoronto.ca/event/operability-of-the-heart-lung-machine/
CATEGORIES:External Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230518T090000
DTEND;TZID=America/Toronto:20230518T100000
DTSTAMP:20230516T203337Z
CREATED:20230515T152033Z
LAST-MODIFIED:20230516T203337Z
UID:10000223-1684400400-1684404000@bme.utoronto.ca
SUMMARY:BME Faculty Search Seminar - Ilke Uguz
DESCRIPTION:Development of High-Density Active Neural Interfaces using Conjugated Polymers\nDr. Ilke Uguz\nPostdoctoral Research Associate\, Columbia University\nPrecise\, stable\, and biocompatible neural interfaces are crucial for effective brain-machine interfaces and therapeutic interventions. Conjugated polymers offer exceptional potential for such applications\, owing to their softness\, biocompatibility\, and mixed ionic and electronic charge transport properties. By integrating CPs at the front-end\, we can achieve active pixels comparable in size to individual neurons while maintaining mechanical properties similar to surrounding tissue. During the talk\, I will delve into microfabrication and design strategies used to develop implantable CP-based neural interfaces with electrical and optical functionalities. Specifically\, I will address the technological challenges associated with scalability and present examples that demonstrate the successful generation of complex circuitries on flexible substrates\, as well as their monolithic integration onto drive electronics. Additionally\, I will demonstrate large-scale electrophysiology and optogenetic manipulation of neuronal circuits with high spatiotemporal resolution\, highlighting the potential of CPs as a foundation for high-density active front-end arrays. \nTalk will be virtual only\, see information below.
URL:https://bme.utoronto.ca/event/bme-faculty-search-seminar-ilke-uguz/
CATEGORIES:BME Faculty Search
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/05/Ilke-Uguz.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230512T063000
DTEND;TZID=America/Toronto:20230512T223000
DTSTAMP:20230404T194420Z
CREATED:20230404T194243Z
LAST-MODIFIED:20230404T194420Z
UID:10000203-1683873000-1683930600@bme.utoronto.ca
SUMMARY:Post-Conference Celebration Dinner and Award Ceremony
DESCRIPTION:BME would like to invite you to the dinner reception at the Royal Ontario Museum (ROM). It has been a crazy last two years and it is a great time for us to get together\, celebrate our achievements\, and meet each other. Students\, faculty\, post-doc\, and administrators will be attending the event. \nThis dinner is free of charge to BME students\, staff\, core faculty members\, and primary cross-appointment faculty members. This will also be extended to non-BME students in core faculty member labs\, research associates in core faculty member labs\, and post-doctoral fellows in core faculty member labs. \nRegister here
URL:https://bme.utoronto.ca/event/post-conference-celebration-dinner-and-award-ceremony/
LOCATION:Royal Ontario Museum\, 100 Queens Park\, Toronto\, ON\, M5S 2C6\, Canada
CATEGORIES:Events & Workshops
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20230512
DTEND;VALUE=DATE:20230513
DTSTAMP:20230404T193452Z
CREATED:20230404T192645Z
LAST-MODIFIED:20230404T193452Z
UID:10000202-1683849600-1683935999@bme.utoronto.ca
SUMMARY:Toronto Biomedical Engineering Conference
DESCRIPTION:Keynote Speakers:\n\n\n\n\n\n\n\n\n\n\n\n\nEhsan Adeli\n\nAssistant Professor\nStanford University \n\n\n\n\n\n\n\n\n\n\nShuichi Takayama\nProfessor\nGeorgia Institute of Technology \n\n\n\n\n\n\n\n\n\n\n\nYasser Iturria Medina\n\nAssistant Professor\nMcGill University \n\n\n\n\n\n\n\n\n\n\n\nTime\nScheduled Activity\nLocation\n\n\n\n\n8:30 – 9:00 am\nBreakfast\nQuad\n\n\n9:00 – 9:15 am\nConference Welcome from BME Director and\nToBE Co-Chairs\nGreat Hall\n\n\n9:15 – 10:15 am\nFirst Keynote Speaker\nGreat Hall\n\n\n10.15-11.15 am\nOral Presentations\nMolecular\nCell & Tissue\nClinical\nEast Common Room\nDebates Room\nMusic Room\n\n\n11.15-11.30 am\nBreak\n\n\n\n11.30 am-12.30 pm\nWorkshop 1: Panel Discussion: Steering\nArtificial Intelligence in Biomedical\nEngineering: Where to draw the line?\nGreat Hall\n\n\n12.30-1.30 pm\nLunch / Posters / Booths\nPosters judged 1.00-1.30\nQuad for Lunch\nEast Common Room &\nMusic Room for Posters\nLower Galley for Booths\n\n\n1.30-2.30 pm\nSecond Keynote\nGreat Hall\n\n\n2.30-3.30 pm\nWorkshop 2: Panel Discussion: Paving your\nCareer Path: Discovering your Calling after\nGraduation\nGreat Hall\n\n\n3.30-3.45\nBreak\n\n\n\n3.45-4.45 pm\nThird Keynote Speaker\nGreat Hall\n\n\n4.45-5.00 pm\nClosing Remarks\nGreat Hall\n\n\n7.00-9.00 pm\nCelebratory Dinner + Awards Ceremony
URL:https://bme.utoronto.ca/event/toronto-biomedical-engineering-conference/
LOCATION:Harthouse\, 7 Hart House Circle\, 7 Hart House Circle\, Toronto
CATEGORIES:Events & Workshops
ORGANIZER;CN="Toronto Biomedical Engineering Conference (ToBE)":MAILTO:tobeconferenceteam@gmail.com
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230503T090000
DTEND;TZID=America/Toronto:20230503T100000
DTSTAMP:20230421T131146Z
CREATED:20230419T152829Z
LAST-MODIFIED:20230421T131146Z
UID:10000215-1683104400-1683108000@bme.utoronto.ca
SUMMARY:BME Faculty Search Seminar - Kibaek Choe
DESCRIPTION:In Vivo Live Cell Imaging by Three-Photon (3P) Microscopy\nDr. Kibaek Choe\,\nPostdoctoral Associate\, Cornell University\nIn vivo confocal and two-photon (2P) microscopies have been a major driving force in deepening our understanding of cell dynamics by enabling the visualization of migration\, distribution\, morphology\, and cell-cell interactions in three dimensions and at subcellular resolution. In this talk\, I will first discuss the key features of confocal and 2P microscopes for in vivo imaging and introduce bio-applications in various mouse organs such as the small intestine\, bone marrow\, and lymph nodes. \nSecondly\, I will talk about 3P microscopy\, which overcomes the depth limitation of confocal and 2P imaging. We applied 3P microscopy to visualize dynamic immune cell behavior in mouse lymph nodes for the first time. We determined safe laser parameters by monitoring immune cell motility in various imaging conditions to prevent photo-damage. Using the safe laser conditions\, we were able to visualize blood vessels through the entire depth of mouse popliteal lymph node in vivo. Additionally\, we could measure the motility of CD4+ and CD8+ T cells through the entire depth of T cell zone in vivo\, allowing us to discover the depth dependence of CD4+ T cell motility in the T cell zone during lipopolysaccharide-induced inflammation. \nThus\, in vivo 3P microscopy has the potential to uncover previously unknown cellular dynamics in deeper regions of many other organs beyond the depth limit of conventional confocal and 2P microscopies. \nTalk will be in-person and virtual\, see information below.
URL:https://bme.utoronto.ca/event/bme-faculty-search-seminar-kibaek-choe/
LOCATION:MS3153
CATEGORIES:BME Faculty Search
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/04/Kibaek-Choe.v4.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230502T120000
DTEND;TZID=America/Toronto:20230502T130000
DTSTAMP:20230417T185715Z
CREATED:20230417T185614Z
LAST-MODIFIED:20230417T185715Z
UID:10000214-1683028800-1683032400@bme.utoronto.ca
SUMMARY:BRI Research Rounds research talk with Dr. Tom Chau
DESCRIPTION:Featured Speaker: Tuesday\, May 2nd\, 2023\, noon to 1 p.m. EST \nWe’re pleased to invite you to hear from our next guest speaker\, Dr. Tom Chau\, a senior scientist\, and a full professor of biomedical engineering at the University of Toronto. He also leads the PRISM Lab (Paediatric Rehabilitation Intelligent Systems Multidisciplinary) \nDr. Chau will present his research talk titled\, Brain-computer interfaces as access technologies for children and youth with disabilities: It’s the thought that counts. \nResearch Talk Summary: \nDr. Chau’s talk will focus on some recent advances in non-invasive brain-computer interfaces (BCIs) developed at Holland Bloorview as an alternative access pathway to communication and environmental control. BCIs directly harness brain activity associated with functional intent and thereby bypass the motor system in connecting people to the world around them. At Holland Bloorview\, we have been investigating near-infrared spectroscopic BCIs\, neuroelectric BCIs\, ultrasonic BCIs and some combinations thereof. Each modality will be briefly introduced\, and a sampling of novel BCI control paradigms will be exemplified. We are only beginning to understand the enabling and therapeutic potential of BCIs in the development of children. The presentation will close with a description of how these technologies are being translated into clinical practice at Holland Bloorview. \nTo register for the event\, visit: hollandbloorview.ca/BRIResearchRounds. \nInterested in learning more about our future speakers? Please email BRIresearchrounds@hollandbloorview.ca to be added to our mailing list.
URL:https://bme.utoronto.ca/event/bri-research-rounds-research-talk-with-dr-tom-chau/
CATEGORIES:External Speaker Series
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/04/Tom-Chau.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230428T123000
DTEND;TZID=America/Toronto:20230428T130000
DTSTAMP:20230427T203725Z
CREATED:20220901T170736Z
LAST-MODIFIED:20230427T203725Z
UID:10000090-1682685000-1682686800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Nafisa Mahbub
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Dr. Warren Chan\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-nafisa-mahbub/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230428T120000
DTEND;TZID=America/Toronto:20230428T123000
DTSTAMP:20230427T203725Z
CREATED:20230419T202235Z
LAST-MODIFIED:20230427T203725Z
UID:10000216-1682683200-1682685000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Christina Jean
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Multimodal Interfaces to Assist Older Adults with Dementia Perform Activities of Daily Living\nAbstract: TBD\nSupervisor Name: Alex Mihailidis\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-christina-jean/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230428T120000
DTEND;TZID=America/Toronto:20230428T123000
DTSTAMP:20230419T202235Z
CREATED:20230419T202235Z
LAST-MODIFIED:20230419T202235Z
UID:10000217-1682683200-1682685000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Christina Jean
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Multimodal Interfaces to Assist Older Adults with Dementia Perform Activities of Daily Living\nAbstract: TBD\nSupervisor Name: Alex Mihailidis\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-christina-jean-2/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230427T123000
DTEND;TZID=America/Toronto:20230427T130000
DTSTAMP:20230426T203728Z
CREATED:20220909T180738Z
LAST-MODIFIED:20230426T203728Z
UID:10000104-1682598600-1682600400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Joseph Sebastian
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Listening to engineered tissues: assessing cellularity\, contractility\, and stiffness using high-frequency ultrasound\nAbstract: TBD\nSupervisor Name: Craig A. Simmons\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-joseph-sebastian/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230427T120000
DTEND;TZID=America/Toronto:20230427T123000
DTSTAMP:20230426T203728Z
CREATED:20220822T165237Z
LAST-MODIFIED:20230426T203728Z
UID:10000037-1682596800-1682598600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Rida Hasan
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Bioadhesion: Reverse Engineering the Adhesion Mechanism of Freshwater Mussels\, The Dresseinids\nAbstract: Currently\, synthetic biocompatible adhesives have been ineffective due to inflammatory reactions or poor strength1. Researchers have attempted to improve upon these adhesives\, but limitations still exist. A synthetic bioadhesives that can function in wet conditions could be a better alternative for tissue reconnections1-2. On the other hand\, many marine and freshwater organisms have adapted to secrete their own holdfast that is resistant to water3. My research aims to understand how freshwater mussels (of the Dresseina genus) adhere to surfaces underwater. Since the adhesion mechanism is largely underexplored in freshwater mussels\, direct translation to a potential bioadhesives will not be the goal of this project. Rather\, elucidating the adhesion mechanism of the freshwater mussel\, Dresseina bugensis\, will be the primary objective. This report presents a biochemical and biophysical approach to elucidate the molecular mechanism of wet adhesion of freshwater mussels. The Dreisseinid byssal proteome and byssal conditions will be described with emphasis on further characterization of Dresseina bugensis foot protein 7 (Dbfp-7) and other adhesive proteins. Characterization of the byssal proteins will provide insight to a potentially novel mechanism of wet adhesion that may improve upon the design requirements of current synthetic wet adhesives.\nSupervisor Name: Eli Sone\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-rida-hasan/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230426T123000
DTEND;TZID=America/Toronto:20230426T130000
DTSTAMP:20230425T202234Z
CREATED:20220831T170759Z
LAST-MODIFIED:20230425T202234Z
UID:10000087-1682512200-1682514000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Seyed-Youns Sadat-Nejad
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Challenging the Labels of Autism and ADHD – A Data-Driven Graph-Based Approach\nAbstract:\nMore than 600\,000 children in Canada are diagnosed with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). These diagnoses are currently based on specific behaviours (e.g.\, social communication difficulties\, inattention)\, which may not correspond to the distinct and unique underlying biology. Moreover\, the labels of ASD and ADHD often do not predict a child’s response to a specific treatment. Instead\, care decisions are made based on each child’s unique behavioural presentation. In many cases\, existing treatments are not effective\, can have adverse side-effects\, and many children continue to experience significant distress and often have poor outcomes as adults (e.g.\, mental health\, employment\, and independence). Collectively\, these challenges suggest that ASD and ADHD may not exist as uniquely-defined diagnostic constructs and highlight the need to discover other groupings that may be more closely aligned with biology and/or response to treatment. To address this need\, the proposed project will perform data-driven approach to question the validity of current diagnostic labels and identify new groupings for children with ASD and ADHD that are biologically relevant. I will do this through an interdisciplinary approach that employs computer science-based machine learning approaches to go beyond traditional analytics methods in this field. The objective of this project is to validate existing groupings or discover new groupings based on unique and distinct biological data. To this\n3\nend\, I will pursue a novel analytical approach: instead of comparing diagnostic groups as currently done\, I use an innovative data-driven approach that looks to the data to discover new groups that transcend the existing diagnostic labels or those that validate the current groups but that also explain why the current treatments are ineffective for many individuals in part because of their adverse side effects. I will do this by use of graph clustering method and graph neural network. This approach is capable of identifying groups who share similar neuroanatomical characteristics/complexities\, regardless of diagnosis.\nSupervisor Name: Dr.Azadeh Kushki\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-seyed-youns-sadat-nejad-2/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230426T120000
DTEND;TZID=America/Toronto:20230426T123000
DTSTAMP:20230425T202234Z
CREATED:20220930T213740Z
LAST-MODIFIED:20230425T202234Z
UID:10000137-1682510400-1682512200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Katsiaryna Kazlovich
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: 3D Printing and Surgical Simulation in Thoracic Surgery\nAbstract: Traditional surgical education is changing at a rapid pace. This shift has been influenced by the widespread adoption and availability of rapid manufacturing methods\, such as 3D printing\, and ever-evolving analytical methods for data acquisition and processing. Since the declaration of the COVID-19 global pandemic\, the modern approach to on-site skill development has had to evolve to accommodate limited access to training due to the risk of exposure and scarcity of resources. In many ways\, these changes serve as a catalyst for innovation\, such as the concept of virtual technical skills education. In this seminar\, I am going to showcase various simulation devices and manufacturing methods that are implemented in surgical skill development and address questions associated with the quantitative and qualitative assessment of skills in senior surgical trainees.\nSupervisor Name: Dr. Kazuhiro Yasufuku\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-katsiaryna-kazlovich/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230425T120000
DTEND;TZID=America/Toronto:20230425T130000
DTSTAMP:20230406T210630Z
CREATED:20230406T210630Z
LAST-MODIFIED:20230406T210630Z
UID:10000210-1682424000-1682427600@bme.utoronto.ca
SUMMARY:BME Student Townhall- Graduate Courses
DESCRIPTION:The BME graduate curriculum committee is reviewing all the graduate courses offered as part of your graduate studies in order to determine whether the current offerings serve you well and whether there are gaps in the offerings.\n\nThus\, the committee would like to consult students in all BME Graduate programs via a Townhall on their experience with the course offerings. Specifically\, the committee is looking to (1) Identify courses that are not popular and the reasons why and (2) Identify courses that students want to take but haven’t been able to (e.g. because they don’t exist\, didn’t fit in schedule\, etc). Additionally\, the committee is looking to present their own suggestions and get feedback from you.\n\nThe Townhall is scheduled for April 25th @ 12-1pm. The event will be hybrid with in-person meeting occurring in MS2173 and zoom information as follows:\n\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\n\nWe invite all students to submit their feedback via this form ahead of the meeting or after if you are unable to attend: https://forms.office.com/r/J7LVH3cZDE
URL:https://bme.utoronto.ca/event/bme-student-townhall-graduate-courses/
LOCATION:MS2173
CATEGORIES:BME Student Townhall
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230421T130000
DTEND;TZID=America/Toronto:20230421T140000
DTSTAMP:20230417T183542Z
CREATED:20230417T183542Z
LAST-MODIFIED:20230417T183542Z
UID:10000212-1682082000-1682085600@bme.utoronto.ca
SUMMARY:BME Faculty Search Seminar - Freeman Lan
DESCRIPTION:Revolutionizing biological discovery through ultrahigh-throughput experimentation\nDr. Freeman Lan\,\nPostdoctoral Fellow\, University of Winsconsin-Madison\nBiological assays have for decades been carried out primarily in reaction tubes and microtiter plates\, which are low throughput and difficult to scale. Microfluidics technology can overcome this limitation through miniaturization of reaction volumes and efficient scaling of liquid handling. I will describe my work pioneering droplet microfluidics as a platform to conduct biological assays at ultrahigh-throughput (>10\,000 assays per run) and how I am now applying this technology to study microbial systems. I show that ultrahigh-throughput experimentation can rapidly generate large amounts of data and bring fresh insights that would previously be unattainable using traditional methods. Given our rapidly increasing capacity to analyze large scale data through advances in machine learning\, ultrahigh-throughput experimentation will become an important way of conducting biological research in the future. \nTalk will be in-person and virtual\, see information below.
URL:https://bme.utoronto.ca/event/bme-faculty-search-seminar-freeman-lan/
LOCATION:MSB 4171
CATEGORIES:BME Faculty Search
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/04/Freeman-Lan.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230421T123000
DTEND;TZID=America/Toronto:20230421T130000
DTSTAMP:20230420T202244Z
CREATED:20230404T180810Z
LAST-MODIFIED:20230420T202244Z
UID:10000201-1682080200-1682082000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Katie Doran
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Gang Zheng\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-katie-doran-2/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230421T120000
DTEND;TZID=America/Toronto:20230421T123000
DTSTAMP:20230420T202244Z
CREATED:20220824T165254Z
LAST-MODIFIED:20230420T202244Z
UID:10000063-1682078400-1682080200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Kai Slaughter
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Molly Shoichet\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-kai-slaughter/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230420T160000
DTEND;TZID=America/Toronto:20230420T170000
DTSTAMP:20230417T185113Z
CREATED:20230417T185113Z
LAST-MODIFIED:20230417T185113Z
UID:10000213-1682006400-1682010000@bme.utoronto.ca
SUMMARY:Copper depletion cancer therapy
DESCRIPTION:Speaker:  \nJianghong Rao\, PhD\nProfessor\, Department of Radiology\nLucas Imaging Center\nStanford University\, California \nHost: Dr. Gang Zheng
URL:https://bme.utoronto.ca/event/copper-depletion-cancer-therapy/
LOCATION:Princess Margaret Cancer Centre\, 610 University Ave\, 6th floor\, Bob Bell Auditorium
CATEGORIES:External Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230420T123000
DTEND;TZID=America/Toronto:20230420T130000
DTSTAMP:20230419T202235Z
CREATED:20220830T170740Z
LAST-MODIFIED:20230419T202235Z
UID:10000083-1681993800-1681995600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Negar Balaghi
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Mechanisms of collective cell migration during Drosophila cardiac morphogenesis\nAbstract: TBD\nSupervisor Name: Rodrigo Fernandez-Gonzalez\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-negar-balaghi/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230420T120000
DTEND;TZID=America/Toronto:20230420T123000
DTSTAMP:20230419T202235Z
CREATED:20220830T170740Z
LAST-MODIFIED:20230419T202235Z
UID:10000084-1681992000-1681993800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Ana Maria Carmo
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Actin regulation in embryonic wound repair\nAbstract: TBD\nSupervisor Name: Rodrigo Fernandez-Gonzalez\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-ana-maria-carmo/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230419T123000
DTEND;TZID=America/Toronto:20230419T130000
DTSTAMP:20230418T200726Z
CREATED:20230103T200744Z
LAST-MODIFIED:20230418T200726Z
UID:10000175-1681907400-1681909200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Megh Rathod
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Development of Accurate and Equitable Wearable Non-Invasive Optical Devices for Continuous Hemodynamic Monitoring\nAbstract:\nThe prevalence of heart failure (HF) is increasing with an estimated 26 million people affected worldwide. Current patient monitoring tools are often inconvenient\, uncomfortable\, and limited in application and accuracy. This has led to the rise of non-invasive continuous monitoring devices\, known as wearables. Advances in wearable technologies are led by miniaturized sensors\, predominantly optoelectronic – which leverage light-tissue interactions to monitor physiology.\nHowever\, existing non-invasive tools rely on numerous assumptions about the physiology of the user\, and often do not account for forms of interpersonal variability (e.g. the presence of melanin in the skin). This work aims to develop optoelectronic strategies for continuous remote monitoring of metrics using multiwavelength (MW) photoplethysmography. To achieve this\, I will implement miniaturized MW spectroscopy platforms into wearable electronic devices and develop algorithms that estimate these physiological metrics and account for interpersonal variability. The custom-developed wearable will use MW photoplethysmography via miniature spectrometers and light sources (across 400 nm – 1000 nm) and will be tested via simulations\, phantoms\, and bench tests before clinical validation.\nThis work will demonstrate a methodology for skin-tone invariant cardiovascular metrics relevant to both clinical-grade and commercial health monitors. Optical sensors will serve a major role in the future of physiological monitoring\, however\, correcting this technology is a key refinement needed to prevent the perpetuation of inaccuracies in marginalized groups. Implementation into a wearable device will allow continuous monitoring of cardiac health that may improve patient outcomes and predict catastrophic events.\nSupervisor Name: Dr. Daniel Franklin (BME) and Dr. Heather Ross (Medicine)\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-megh-rathod/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230419T120000
DTEND;TZID=America/Toronto:20230419T123000
DTSTAMP:20230418T200726Z
CREATED:20221003T213809Z
LAST-MODIFIED:20230418T200726Z
UID:10000139-1681905600-1681907400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Hrishikesh Suresh
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Optimizing Response to Neuromodulation\nAbstract: Epilepsy is the most common and debilitating disorder of childhood. Children with epilepsy have mortality rates three times higher than the general population and experience significant morbidity\, including injuries and hospitalizations. One treatment option for children who have uncontrolled seizures is vagus nerve stimulation (VNS). This surgical procedure involves the implantation of an electric pulse generator to deliver stimulation to the vagus nerve at the level of the neck. However\, only 25-50% of patients achieve meaningful improvement in their seizure burden after VNS. Consequently\, many children undergo the risk of surgery without benefit. Furthermore\, the inability to identify children most likely to benefit results in inefficient allocation of Canadian healthcare resources and precludes care for other children who may be better candidates for VNS. There is\, therefore\, a critical and unmet need to develop novel means to pre-surgically predict seizure reduction following VNS. This work leverages advances in brain network mapping and machine learning to test the hypothesis that differences in brain network organization can predict outcomes following VNS\, and consequently\, identify ideal candidates for surgical intervention.\nSupervisor Name: Dr. George Ibrahim & Dr. James Drake\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-hrishikesh-suresh/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230418T130000
DTEND;TZID=America/Toronto:20230418T140000
DTSTAMP:20230414T202721Z
CREATED:20230413T144237Z
LAST-MODIFIED:20230414T202721Z
UID:10000211-1681822800-1681826400@bme.utoronto.ca
SUMMARY:BME Faculty Search Seminar - Tian He\, Harvard University
DESCRIPTION:Illuminating Bioelectricity in the Brain\nDr. He Tian\,\nPostdoctoral Associate\, Harvard University\nThe brain encodes and processes information through the dynamic membrane voltage of neurons. However\, in vivo electrophysiology\, i.e.\, the study of the membrane voltage of individual cells in live animals\, has been a major challenge for neuroscience. In this seminar\, I will present voltage imaging\, an emerging technology using genetically encoded voltage indicators (GEVIs) to visualize the membrane voltage dynamics of cells. Voltage imaging can be combined with optogenetic stimulation to enable “all-optical electrophysiology”\, a technology that enabled cell membrane voltage to be simultaneously recorded and perturbed with light\, opening a path for high-throughput electrophysiology study in live animals. Thus far\, the performance of GEVIs has been a bottleneck for many applications. I will describe my directed evolution effort to improve a far-red GEVI. In order to optimize the transient voltage response of this biosensor\, I developed a novel video-based pooled screening platform that enabled thousands of genetic variants to be screened expeditiously. Using this platform\, I developed far-red GEVIs with improved signal-to-noise ratios and kinetics. Importantly\, this platform may be adapted for many types of genetic screens where optical readouts are required. I will discuss the application of these new GEVIs for tracking electric signal propagation within neurons. In particular\, I will demonstrate how to use voltage imaging and all-optical electrophysiology to understand neuron network dynamics in the live mouse brain. Together\, these molecular and optical tools will greatly expand our ability to decipher the brain. \nTalk will be in-person and virtual\, see information below.
URL:https://bme.utoronto.ca/event/bme-faculty-search-seminar-tian-he-harvard-university/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:BME Faculty Search
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/04/Tian-He-faculty-search.jpg
END:VEVENT
END:VCALENDAR