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X-WR-CALNAME:Institute of Biomedical Engineering (BME)
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X-WR-CALDESC:Events for Institute of Biomedical Engineering (BME)
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TZID:America/Toronto
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TZOFFSETFROM:-0500
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DTSTART:20220313T070000
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BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230420T160000
DTEND;TZID=America/Toronto:20230420T170000
DTSTAMP:20230417T185113Z
CREATED:20230417T185113Z
LAST-MODIFIED:20230417T185113Z
UID:10000213-1682006400-1682010000@bme.utoronto.ca
SUMMARY:Copper depletion cancer therapy
DESCRIPTION:Speaker:  \nJianghong Rao\, PhD\nProfessor\, Department of Radiology\nLucas Imaging Center\nStanford University\, California \nHost: Dr. Gang Zheng
URL:https://bme.utoronto.ca/event/copper-depletion-cancer-therapy/
LOCATION:Princess Margaret Cancer Centre\, 610 University Ave\, 6th floor\, Bob Bell Auditorium
CATEGORIES:External Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230420T123000
DTEND;TZID=America/Toronto:20230420T130000
DTSTAMP:20230419T202235Z
CREATED:20220830T170740Z
LAST-MODIFIED:20230419T202235Z
UID:10000083-1681993800-1681995600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Negar Balaghi
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Mechanisms of collective cell migration during Drosophila cardiac morphogenesis\nAbstract: TBD\nSupervisor Name: Rodrigo Fernandez-Gonzalez\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-negar-balaghi/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230420T120000
DTEND;TZID=America/Toronto:20230420T123000
DTSTAMP:20230419T202235Z
CREATED:20220830T170740Z
LAST-MODIFIED:20230419T202235Z
UID:10000084-1681992000-1681993800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Ana Maria Carmo
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Actin regulation in embryonic wound repair\nAbstract: TBD\nSupervisor Name: Rodrigo Fernandez-Gonzalez\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-ana-maria-carmo/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230419T123000
DTEND;TZID=America/Toronto:20230419T130000
DTSTAMP:20230418T200726Z
CREATED:20230103T200744Z
LAST-MODIFIED:20230418T200726Z
UID:10000175-1681907400-1681909200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Megh Rathod
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Development of Accurate and Equitable Wearable Non-Invasive Optical Devices for Continuous Hemodynamic Monitoring\nAbstract:\nThe prevalence of heart failure (HF) is increasing with an estimated 26 million people affected worldwide. Current patient monitoring tools are often inconvenient\, uncomfortable\, and limited in application and accuracy. This has led to the rise of non-invasive continuous monitoring devices\, known as wearables. Advances in wearable technologies are led by miniaturized sensors\, predominantly optoelectronic – which leverage light-tissue interactions to monitor physiology.\nHowever\, existing non-invasive tools rely on numerous assumptions about the physiology of the user\, and often do not account for forms of interpersonal variability (e.g. the presence of melanin in the skin). This work aims to develop optoelectronic strategies for continuous remote monitoring of metrics using multiwavelength (MW) photoplethysmography. To achieve this\, I will implement miniaturized MW spectroscopy platforms into wearable electronic devices and develop algorithms that estimate these physiological metrics and account for interpersonal variability. The custom-developed wearable will use MW photoplethysmography via miniature spectrometers and light sources (across 400 nm – 1000 nm) and will be tested via simulations\, phantoms\, and bench tests before clinical validation.\nThis work will demonstrate a methodology for skin-tone invariant cardiovascular metrics relevant to both clinical-grade and commercial health monitors. Optical sensors will serve a major role in the future of physiological monitoring\, however\, correcting this technology is a key refinement needed to prevent the perpetuation of inaccuracies in marginalized groups. Implementation into a wearable device will allow continuous monitoring of cardiac health that may improve patient outcomes and predict catastrophic events.\nSupervisor Name: Dr. Daniel Franklin (BME) and Dr. Heather Ross (Medicine)\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-megh-rathod/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230419T120000
DTEND;TZID=America/Toronto:20230419T123000
DTSTAMP:20230418T200726Z
CREATED:20221003T213809Z
LAST-MODIFIED:20230418T200726Z
UID:10000139-1681905600-1681907400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Hrishikesh Suresh
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Optimizing Response to Neuromodulation\nAbstract: Epilepsy is the most common and debilitating disorder of childhood. Children with epilepsy have mortality rates three times higher than the general population and experience significant morbidity\, including injuries and hospitalizations. One treatment option for children who have uncontrolled seizures is vagus nerve stimulation (VNS). This surgical procedure involves the implantation of an electric pulse generator to deliver stimulation to the vagus nerve at the level of the neck. However\, only 25-50% of patients achieve meaningful improvement in their seizure burden after VNS. Consequently\, many children undergo the risk of surgery without benefit. Furthermore\, the inability to identify children most likely to benefit results in inefficient allocation of Canadian healthcare resources and precludes care for other children who may be better candidates for VNS. There is\, therefore\, a critical and unmet need to develop novel means to pre-surgically predict seizure reduction following VNS. This work leverages advances in brain network mapping and machine learning to test the hypothesis that differences in brain network organization can predict outcomes following VNS\, and consequently\, identify ideal candidates for surgical intervention.\nSupervisor Name: Dr. George Ibrahim & Dr. James Drake\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-hrishikesh-suresh/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230418T130000
DTEND;TZID=America/Toronto:20230418T140000
DTSTAMP:20230414T202721Z
CREATED:20230413T144237Z
LAST-MODIFIED:20230414T202721Z
UID:10000211-1681822800-1681826400@bme.utoronto.ca
SUMMARY:BME Faculty Search Seminar - Tian He\, Harvard University
DESCRIPTION:Illuminating Bioelectricity in the Brain\nDr. He Tian\,\nPostdoctoral Associate\, Harvard University\nThe brain encodes and processes information through the dynamic membrane voltage of neurons. However\, in vivo electrophysiology\, i.e.\, the study of the membrane voltage of individual cells in live animals\, has been a major challenge for neuroscience. In this seminar\, I will present voltage imaging\, an emerging technology using genetically encoded voltage indicators (GEVIs) to visualize the membrane voltage dynamics of cells. Voltage imaging can be combined with optogenetic stimulation to enable “all-optical electrophysiology”\, a technology that enabled cell membrane voltage to be simultaneously recorded and perturbed with light\, opening a path for high-throughput electrophysiology study in live animals. Thus far\, the performance of GEVIs has been a bottleneck for many applications. I will describe my directed evolution effort to improve a far-red GEVI. In order to optimize the transient voltage response of this biosensor\, I developed a novel video-based pooled screening platform that enabled thousands of genetic variants to be screened expeditiously. Using this platform\, I developed far-red GEVIs with improved signal-to-noise ratios and kinetics. Importantly\, this platform may be adapted for many types of genetic screens where optical readouts are required. I will discuss the application of these new GEVIs for tracking electric signal propagation within neurons. In particular\, I will demonstrate how to use voltage imaging and all-optical electrophysiology to understand neuron network dynamics in the live mouse brain. Together\, these molecular and optical tools will greatly expand our ability to decipher the brain. \nTalk will be in-person and virtual\, see information below.
URL:https://bme.utoronto.ca/event/bme-faculty-search-seminar-tian-he-harvard-university/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:BME Faculty Search
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/04/Tian-He-faculty-search.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230414T123000
DTEND;TZID=America/Toronto:20230414T130000
DTSTAMP:20230413T195231Z
CREATED:20220914T210735Z
LAST-MODIFIED:20230413T195231Z
UID:10000119-1681475400-1681477200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Qin Ji
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Investigating the relationship between tumour metabolism and nanoparticle accumulation\nAbstract:\nCancer is one of the leading causes of death in the world. The principle has guided nanoparticles designed for\ncancer treatment that nanoparticle transport into the tumour is a passive and concentration-driven process.\nRecent studies have found that nanoparticle transport into tumours is predominantly an active process.\nUnderstanding the driving force of this active transport enables us to design the next generation of\nnanoparticles. Metabolism describes all the energy-producing processes in a biological system. As tumours\ngrow\, their need for nutrients and other building blocks increases. This may lead to nonspecific uptake of\navailable resources circulating in the tumour blood vessels. The objective of the proposed thesis is to answer\nthe question: does tumour metabolism drive nanoparticle accumulation? The result of this project will\ndescribe a relationship between tumour nanoparticle accumulation and tumour metabolic activity. The\nsignificance of this study defines the mechanistic cause of nanoparticle transport into tumours under the new\nparadigm. This understanding enables us to exploit metabolism to increase the effectiveness of nanoparticle\ndrug carriers for cancer treatment. For example\, we may manipulate a patient’s diet to increase nanoparticle\ndelivery to solid tumours. This strategy can lead to higher drug delivery and more effective cancer treatment.\nSupervisor Name: Warren Chan\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-qin-ji/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230414T120000
DTEND;TZID=America/Toronto:20230414T123000
DTSTAMP:20230413T195231Z
CREATED:20230406T182229Z
LAST-MODIFIED:20230413T195231Z
UID:10000209-1681473600-1681475400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Gabriel Ng
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Jan Andrysek\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-gabriel-ng/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230413T123000
DTEND;TZID=America/Toronto:20230413T130000
DTSTAMP:20230412T195231Z
CREATED:20220913T210755Z
LAST-MODIFIED:20230412T195231Z
UID:10000115-1681389000-1681390800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Liyang Zhong
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Investigating the Molecular Control of Collagen Biomineralization\nAbstract: Mineralized collagen fibrils are the basic building blocks of various mineralized connective tissues. The process of collagen biomineralization is an intricate and highly controlled process which makes it difficult to study in vivo. To date\, many in vitro models have been developed aiming to understand and mimic native collagen biomineralization. However\, despite the recent advances\, the molecular control of collagen biomineralization still remains unclear. I aim to study the effect of chemical and enzymatic collagen crosslinking\, as well as the effect of glycosaminoglycan\, an extracellular biomolecule\, on collagen biomineralization. Findings from this study will result in an effective in vitro model that can highly mimic native collagen. It will also help with the development of collagen-based materials that will benefit tissue repair and regeneration applications.\nSupervisor Name: Eli Sone\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-liyang-zhong/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230413T120000
DTEND;TZID=America/Toronto:20230413T123000
DTSTAMP:20230412T195231Z
CREATED:20220825T165236Z
LAST-MODIFIED:20230412T195231Z
UID:10000069-1681387200-1681389000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Chuan Liu
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Milica Radisic\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-chuan-liu/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230412T123000
DTEND;TZID=America/Toronto:20230412T130000
DTSTAMP:20230411T194729Z
CREATED:20220830T170740Z
LAST-MODIFIED:20230411T194729Z
UID:10000082-1681302600-1681304400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Craig Macsemchuk
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: A Magnetic Resonance Imaging Guided High Intensity Focused Ultrasound Platform for Fetal Interventions\nAbstract:\nBackground:\nCongenital abnormalities cause 20% of all perinatal deaths in North America\, where some\nrequire fetal intervention to improve outcomes . Due to routine ultrasound imaging during\npregnancy\, most fetal anomalies are detected before birth; however\, many are progressive before\nbirth\, leading to fetal death . All current options for fetal therapy involve entering the\namniotic sac for surgical procedures\, which carry a significant risk of premature birth due to\nmembrane rupture . Ultrasound energy creates no incision and is non-ionizing\, therefore\, it\nreduces the risk of infection and does not damage adjacent non-targeted tissues. These attributes\nmake it an ideal modality for fetal surgical interventions. Magnetic resonance-guided high\nintensity focused ultrasound (MRgHIFU) is a non-invasive therapy modality that is clinically\napproved in Canada to treat uterine fibroids\, bone metastasis and essential tremor. All currently\navailable MRgHIFU devices generate ultrasound energy from a transducer integrated into a\npurpose-built MRI table. This ultrasound energy source transmits upward\, focusing into the\npatient\, and creating a thermal lesion as small as a grain of rice (8x2x2mm). This focal point can\nbe mechanically and electronically steered to cover a large treatment volume. However\, in these\napproved devices\, the ultrasound energy sources are situated so they cannot accommodate a\npregnant mother and therefore are not conducive to an ergonomically feasible or safe treatment\nof fetuses. A pregnant mother cannot lay on her stomach in a prone position. Such is the rational\nfor developing an MRgHIFU robot that brings the ultrasound energy source to the pregnant\nmother inside an MRI scanner in such a way that she can lay on her back in a supine position.\nObjective and Hypothesis:\nThe objective of this project is to design and build an MRgHIFU robot for fetal interventions\nthat can accommodate a pregnant mother. My hypothesis is that robotic positioning of\nultrasound energy will demonstrate that MRIgHIFU is safe\, effective\, and feasible for treating\ncongenital fetal defects.\nMethods:\nI will achieve my objective by: 1) Designing and developing an MRgHIFU platform for fetal\napplications. This will incorporate MRgHIFU infrastructure in our laboratory at SickKids  and\ncreate an MRgHIFU robot that brings the ultrasound transducer to the patient to accommodate\nprenatal interventions. 2) Assessing the workspace range and targeting accuracy of the produced\nMRgHIFU robot in phantoms to ensure it performs appropriately for fetal interventions.\n3) Demonstrating the safety and efficacy of the produced robot by ablating multiple targets in\nour lab’s established pregnant rabbit model . This will consist of an MRgHIFU survival study\nin a pregnant rabbit model targeting placental and fetal lung\, kidney\, liver\, and heart tissues.\nSignificance of the research:\nDeveloping an MRIgHIFU robot for fetal therapies is critical for making it available to pregnant\npatients. Our lab’s partnership with Profound Medical\, a HIFU device company with experience\nreleasing multiple clinical devices\, will allow the developed robot to become accessible to\npatients in the future. The availability of MRIgHIFU in a clinical setting can decrease the risk of\ncomplications in fetal therapies\, lead to better patient outcomes\, shorter patient recovery times\nand also reduce the average healthcare cost attributed to fetal surgery.\nSupervisor Name: James Drake\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-craig-macsemchuk/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230406T123000
DTEND;TZID=America/Toronto:20230406T130000
DTSTAMP:20230405T182302Z
CREATED:20220824T165254Z
LAST-MODIFIED:20230405T182302Z
UID:10000061-1680784200-1680786000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Chun-Yu Lin
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Lidan You\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-chun-yu-lin/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230406T120000
DTEND;TZID=America/Toronto:20230406T123000
DTSTAMP:20230405T182302Z
CREATED:20221107T203740Z
LAST-MODIFIED:20230405T182302Z
UID:10000156-1680782400-1680784200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Minyao Wang
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Sticky conductive membrane relieves atrial fibrillation: efficacy analysis\nAbstract: Atrial fibrillation (AF) is the most common form of cardiac arrhythmia\, significantly contributing to public health care expenditure and cardiovascular disease-related mortality. While the mechanisms remain unclear; more evidence has been found to support the spiral wave theory of AF persistence\, stating that a high-frequency reentrant circuit originating from the singularity could act as a relatively stable source of disturbed conduction\, which would eventually lead to the development of the fibrillation burden. Targeting the electrophysiological features of biological tissues\, biomaterial has emerged in recent decades with promising potentials. We have focused on studying the novel conductive biomaterial in cardiac applications to facilitate the propagation of the electrical signals between cardiomyocytes that are physically separated due to structural and functional electrical blockages\, including fibrotic scarring. In this study\, I hypothesized that the use of conductive biomaterial could facilitate the biological action potential propagation between physically isolated cardiomyocytes\, which can then lead to the relief of the rotor-originated spiral electrical waves to relieve the atrial fibrillation burdens. More specifically\, a conductive sticky bilayer Gel-PDA membrane is implanted to the right atrial surface of the Lkb1 knockout transgenic AF mouse models to target the electrophysiological pathogenesis of atrial fibrillation. Here\, the efficacy evaluation is performed by the in Vivo surface electrocardiogram\, echocardiogram\, and the programmed electric stimulation (PES) based arrhythmia susceptibility test.\nSupervisor Name: Dr. Ren-ke Li\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-minyao-wang/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230405T123000
DTEND;TZID=America/Toronto:20230405T130000
DTSTAMP:20230404T180810Z
CREATED:20220824T165254Z
LAST-MODIFIED:20230404T180810Z
UID:10000060-1680697800-1680699600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Nhien Tran-Nguyen
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Computational Fluid Dynamics to Investigate the Relation Between Hemodynamics and Coronary Artery Bypass Graft Failure\nAbstract: TBD\nSupervisor Name: Piero Triverio\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-nhien-tran-nguyen/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230405T120000
DTEND;TZID=America/Toronto:20230405T123000
DTSTAMP:20230404T180810Z
CREATED:20220819T163756Z
LAST-MODIFIED:20230404T180810Z
UID:10000038-1680696000-1680697800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Daniela Chan-Viquez
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Video gaming for home-based rehabilitation: feasibility for children with hemiplegic cerebral palsy living in Costa Rica.\nAbstract: Economic and geographic barriers can limit access to rehabilitation therapies for children with cerebral palsy (CP). These barriers are magnified in developing countries and with the recent COVID-19 pandemic. In Costa Rica\, 43% of children with disabilities do not have access to basic health services. To address this accessibility gap\, effective and engaging approaches are needed to motivate and support children in practicing motor therapies at home. Bootle Blast (BB) is a low-cost\, movement-tracking video game encouraging upper limb (UL) exercises at home. This study will assess the feasibility of a family-centred BB home intervention among Costa Rican children with CP. Our objectives are to 1) Establish probable efficacy for clinical outcomes related to UL function\, activity\, and participation and 2) Evaluate the implementation of the 8-week BB intervention (e.g.\, achievement of family-directed play time goals). Fifteen children with a diagnosis of CP (7-17 yrs) and one of their primary caregivers will participate. Children must have a current accessibility barrier to UL rehabilitation services as reported by the caregiver. Study assessments will be performed via videoconference (probable efficacy). Measures will target UL activity (e.g.\, Box & Blocks Test) and related participation (i.e.\, Canadian Occupational Performance Measure). Children will play BB at home for 8 weeks with weekly\, 15–20-minute check-in video calls by a monitoring therapist. Computer-system logs (e.g.\, time and games played) and data from reported technical barriers will be collected (implementation). Measures for implementation will be reported using descriptive statistics. System logs will identify the percentage of children meeting their weekly play time goal. Effect sizes and confidence intervals will be calculated for clinical measures. Pre-post changes in clinical outcomes will be interpreted based on the minimal clinically important difference (MCID). This study will provide valuable learnings on how therapy gaming interventions can/should be implemented to bridge accessibility gaps\, engage children and caregivers\, and improve access to care.\nSupervisor Name: Elaine Biddiss\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-daniela-chan-viquez/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230331T123000
DTEND;TZID=America/Toronto:20230331T130000
DTSTAMP:20230330T173744Z
CREATED:20220901T170736Z
LAST-MODIFIED:20230330T173744Z
UID:10000089-1680265800-1680267600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - bram bussin
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Warren Chan\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-bram-bussin/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230331T120000
DTEND;TZID=America/Toronto:20230331T123000
DTSTAMP:20230330T173744Z
CREATED:20220901T170736Z
LAST-MODIFIED:20230330T173744Z
UID:10000088-1680264000-1680265800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Colin Blackadar
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Tbd\nAbstract: Tbd\nSupervisor Name: Warren Chan\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-colin-blackadar/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230330T123000
DTEND;TZID=America/Toronto:20230330T130000
DTSTAMP:20230329T172322Z
CREATED:20221011T220810Z
LAST-MODIFIED:20230329T172322Z
UID:10000147-1680179400-1680181200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Omar Mourad
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Modeling HFpEF-like diastolic dysfunction in a heart-on -a-chip platform\nAbstract: TBD\nSupervisor Name: Sara Vasconcelos\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-omar-mourad/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230330T120000
DTEND;TZID=America/Toronto:20230330T123000
DTSTAMP:20230329T172322Z
CREATED:20220825T165236Z
LAST-MODIFIED:20230329T172322Z
UID:10000068-1680177600-1680179400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Safwat Khan
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Defining and validating a pancreatic tissue-specific endothelial cell transcriptional signature\nAbstract: The vasculature shows intricate tissue-specific structural and functional heterogeneity. Vessels in the pancreas display specialized structures\, called fenestrae\, which allow for rapid glucose sensing and response by insulin secreting β-cells. Moreover\, intra-islet ECs have been implicated in a unique cross-talk with β-cells\, which is essential for their survival and function. We reasoned that a unique\, pancreas-specific molecular signature enables ECs to adopt a pancreatic-specific microvascular identity\, specializing them to support glucose/Islet function and homeostasis. To uncover this signature\, we have performed a meta-analysis of published single-cell and single-nuclei RNA-sequencing datasets of the pancreas. Using multi-organ gene expression atlases we have uncovered and validated a pancreas-specific endothelial gene signature. We also introduce a transcriptomic map of human pancreatic ECs integrating 3 human pancreas EC datasets. We define gene signatures for different vascular bed segments within the pancreas\, including 2 unique capillary populations\, which are reminiscent of exocrine pancreas ECs and islet-like/endocrine ECs. We have validated our transcriptomic profile using RNAScope and immunofluorescence staining on mouse e18.5 pancreatic tissue cross-sections. Further characterization of our pancreas-specific endothelial gene signatures and vascular subtype signatures within the pancreas will provide novel insights into the molecular mechanisms that drive islet EC specialization in glucose homeostasis and their role in diabetes.\nSupervisor Name: Sara Vasconcelos\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-safwat-khan/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230329T123000
DTEND;TZID=America/Toronto:20230329T130000
DTSTAMP:20230328T172229Z
CREATED:20221124T192233Z
LAST-MODIFIED:20230328T172229Z
UID:10000161-1680093000-1680094800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Lindsay Stern
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: A Novel Approach for Body Position Monitoring during Sleep using a Smart Mat\nAbstract: TBD\nSupervisor Name: Atena Roshan-Fekr\, Geoff Fernie\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-lindsay-stern/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230329T120000
DTEND;TZID=America/Toronto:20230329T123000
DTSTAMP:20230328T172229Z
CREATED:20221102T203737Z
LAST-MODIFIED:20230328T172229Z
UID:10000154-1680091200-1680093000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Yupeng Tian
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: A Firing Rate Network Model on the Thalamic Deep Brain Stimulation\nAbstract:\nDeep brain stimulation (DBS) is a standardized therapy of many neurological motion disorders\, e.g.\, Parkinson’s disease and essential tremor. However\, the DBS therapeutic mechanisms on the disease-related neuronal networks remain elusive. DBS mechanism detection is challenging due to insufficient quantitative understandings and the sparsity of human data. For human subjects\, neuronal data can only be recorded with safe parameter settings on a very small proportion of neurons.\nWe developed a firing rate network model on the neuronal circuits receiving DBS\, and implemented the model in investigating the network mechanism underlying the thalamus-DBS in treating essential tremor. We accurately reproduced the experimental single-unit recordings on the neurons in thalamic ventral intermediate nucleus (Vim) during DBS; the model fit is precise and consistent across various DBS frequencies (5~200Hz). We found the role of inhibitory nuclei is critical in stabilizing the network and accurately fitting the experimental data. Our model can be potentially implemented in optimizing the DBS frequencies for maximal clinical effects.\nSupervisor Name: Milos Popovic and Milad Lankarany\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-yupeng-tian/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230324T123000
DTEND;TZID=America/Toronto:20230324T130000
DTSTAMP:20230323T172253Z
CREATED:20230323T172253Z
LAST-MODIFIED:20230323T172253Z
UID:10000200-1679661000-1679662800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Jurgen Frasheri
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Development a Limulus Amoebocyte Lysate Assay for Bacterial Endotoxin Testing on a Digital Microfluidic Platform\nAbstract:\nBacterial endotoxin is a pyrogenic substance that can trigger a severe immune response\, resulting in death. The Limulus amoebocyte lysate (LAL) assay\, derived from the blood of horseshoe crabs\, is the globally approved gold standard method for detecting endotoxin. The pharmaceutical and biomedical industries conduct regular endotoxin checks\, and the increased demand for LAL has led to a significant decline in horseshoe crab populations worldwide. In light of this\, we propose a digital microfluidics (DMF) method that minimizes reagent consumption to address this issue. Our approach uses less than 1 μL of LAL reagent per test\, representing a 100x to 1000x reduction in volume compared to traditional methods.\nTo detect bacterial endotoxin\, I am introducing an image-based and capacitance-based method that can reduce the total assay time. However\, to make these assays practical and minimize the risk of contamination\, I plan to develop an enclosure that integrates seamlessly with the endotoxin assay workflow. My goal is to provide optimal incubation conditions and mitigate potential sources of contamination\, making the assay workflow easy to use.\nSupervisor Name: Aaron Wheeler\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-jurgen-frasheri/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230324T120000
DTEND;TZID=America/Toronto:20230324T123000
DTSTAMP:20230323T172253Z
CREATED:20220916T212233Z
LAST-MODIFIED:20230323T172253Z
UID:10000120-1679659200-1679661000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Anish Jadav
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: IFNa as a potential anti-tumour therapeutic\nAbstract: There is significant clinical precedence for the use of IFNa as an anti-tumour therapeutic. However\, these uses are hampered by toxicities associated with high-dose/high-frequency regimens\, and by the immune-evasive properties of the tumour environment. Herein\, we demonstrate how IFNa expressed by tumour cells can prevent tumour formation in vivo\, with no observable toxicities. However\, this rejection does not result in protective effects against a subsequent rechallenge of the tumour cell line. These results demonstrate the utility of IFNa as an anti-tumour therapeutic\, though indicate that the mechanism by which the tumour cells are being rejected does not result in protective immunity against cancer\, thereby limiting the use of IFNa as a monotherapy against cancer.\nSupervisor Name: Dr. Kevin Truong\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-anish-jadav/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230323T123000
DTEND;TZID=America/Toronto:20230323T130000
DTSTAMP:20230322T170732Z
CREATED:20220825T165236Z
LAST-MODIFIED:20230322T170732Z
UID:10000067-1679574600-1679576400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Keyu Zhuang
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Novel Magnetic Resonance Imaging Approach for In-vivo Long-term Stem Cell Tracking\nAbstract:\nMany tissues and organs in the human body\, such as the heart and the brain\, cannot regenerate after injury or disease. Stem cells are a source for regeneration\, as they are self-renewing and can become diverse specialized cell types. Currently\, when stem cells are injected into the body\, there is no information on whether or not they survive\, grow\, and contribute to improved tissue function until histology is performed. While this approach can be adopted in animal studies\, it nonetheless precludes probing cell viability\, retention\, distribution\, and interaction with host tissue in a temporal manner. A technology that enables non-invasive cell tracking in deep tissue would address these hurdles and pave the way for stem cell treatment optimization and translation.\nThe main objective of this project is to develop and apply a novel magnetic resonance imaging (MRI) cell tracking platform for non-invasive\, high resolution visualization\, monitoring\, and evaluation of therapeutic stem cells inside a living subject. In the current research\, we develop and apply our cell tracking platform to human embryonic stem cells (hESC)-derived cardiomyocytes for cardiac regeneration. The stem cells will be “labeled” by inserting a reporter gene into the genome. When the edited cells are exposed to MR-active metal ions\, the cells will light up on MRI.\nSupervisor Name: Hai-Ling Margaret Cheng\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-keyu-zhuang/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230323T120000
DTEND;TZID=America/Toronto:20230323T123000
DTSTAMP:20230322T170732Z
CREATED:20220824T165254Z
LAST-MODIFIED:20230322T170732Z
UID:10000059-1679572800-1679574600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Chantal Trepanier
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Development of a Biodegradable Polymeric Nanoparticle Vascular Delivery System for Therapeutic Peptides\nAbstract: Balloon angioplasty\, often in conjunction with stenting\, is the current standard of care to restore immediate blood flow in arteries affected by atherosclerosis. However\, long-term prevention of arterial re-occlusion\, known as restenosis\, is lacking. Persistent inflammation\, heightened immunogenicity\, neointimal hyperplasia\, and poor reendothelialization remain significant barriers to effective treatment. The proposed research investigates noninflammatory biodegradable nanoparticles as an excipient for therapeutic peptides that can be coupled with traditional endovascular balloon angioplasty techniques to address these longterm treatment concerns. Therapeutic peptide coated nanoparticles incorporated onto an endovascular balloon are hypothesized to establish a sustained controlled release of peptide capable of inhibiting smooth muscle cell migration without compromising vessel reendothelialization upon release from the balloon surface.\nSupervisor Name: Dr. Paul Santerre\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-chantal-trepanier/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230322T123000
DTEND;TZID=America/Toronto:20230322T130000
DTSTAMP:20230321T170741Z
CREATED:20220825T165236Z
LAST-MODIFIED:20230321T170741Z
UID:10000066-1679488200-1679490000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Guijin Li
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Can baseline sEMG predict strength recovery of upper extremity muscles undergoing FES therapy after cervical SCI?\nAbstract: TBD\nSupervisor Name: Prof. José Zariffa\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-guijin-li/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230322T120000
DTEND;TZID=America/Toronto:20230322T123000
DTSTAMP:20230321T170741Z
CREATED:20220824T165254Z
LAST-MODIFIED:20230321T170741Z
UID:10000058-1679486400-1679488200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Kaylie Lau
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: A Novel Method for the Prediction of Slip-Resistance Quality of Winter Footwear\nAbstract: N/A\nSupervisor Name: Dr. Atena Roshan Fekr and Dr. Geoff Fernie\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-kaylie-lau/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230317T123000
DTEND;TZID=America/Toronto:20230317T130000
DTSTAMP:20230316T170824Z
CREATED:20230207T212237Z
LAST-MODIFIED:20230316T170824Z
UID:10000192-1679056200-1679058000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Ryan Lee
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Towards neural-network-on-a-chip: integrating microfluidics with DNA-based computers for powerful point-of-care diagnostics\nAbstract:\nMachine learning can diagnose diseases based on the amount of different RNA present in patient samples. However\, this requires costly computers\, equipment\, and trained operators. DNA-based computers are a cheap and accessible alternative for reading and processing patient RNA. Currently\, DNA computers are limited in processing power due to “leak”\, interference from two interacting signals. By designing DNA computers that integrate with microfluidic devices\, we can overcome leak for powerful point-of-care diagnostics.\nHere we introduce DNA-based biomolecular neurons for low-cost machine-learning-capable DNA computers. These neurons assemble together to form in vitro neural networks. First\, we use enzymes to create highly pure DNA components to reduce leak. Second\, we immobilize the DNA strands onto magnetic beads for modular assembly. DNA by-products from neuron assembly and computation can then be removed from solution using magnets\, further reducing leak. This immobilization also allows us to synchronize computation across each layer of the neural network. Integration with microfluidics will replace manual magnetic separation with automated fluid exchange\, allowing massively parallel computing for neural-network-on-a-chip.\nWe demonstrate proof-of-concept for biomolecular neurons and enzymatic synthesis through modular primer mix-and-match and nucleic acid hybridization. We show synthesis of 6 unique species of neurons with input-specific actuation and high purity\, requiring only 2 hours of preparation from start to finish. Our neurons actuate quickly\, in less than 15 minutes\, with 8-fold signal-to-background ratio\, and are capable of making synaptic connections with up to 10 other neurons. Furthermore\, we demonstrate self-assembly of these biomolecular neurons into computational layers\, and show basic neural network features\, such as neuron cascading\, fan-in and fan-out motifs.\nOur proposed design enables computer-free neural networks for complex decision making in portable diagnostics\, autonomous lab-on-a-chips\, compact data storage\, and development of other in vitro neural network architectures. We plan for near future integration with microfluidic devices to bring further programmability and ease of operation to DNA-based computing.\nSupervisor Name: Leo Chou\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-ryan-lee/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230317T120000
DTEND;TZID=America/Toronto:20230317T123000
DTSTAMP:20230316T170824Z
CREATED:20220930T213739Z
LAST-MODIFIED:20230316T170824Z
UID:10000136-1679054400-1679056200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Meghan Rothenbroker
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Leo Chou\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-meghan-rothenbroker/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230316T160000
DTEND;TZID=America/Toronto:20230316T170000
DTSTAMP:20230315T175542Z
CREATED:20230315T175542Z
LAST-MODIFIED:20230315T175542Z
UID:10000199-1678982400-1678986000@bme.utoronto.ca
SUMMARY:Targeting Tumor Extracellular Matrix for Precision Cancer Imaging and Therapy
DESCRIPTION:Speaker:  \nZheng-Rong Lu\, PhD\nProfessor\, Department of Biomedical Engineering\,\nCase Western Reserve University\,\nCleveland\, Ohio \nHost: Dr. Gang Zheng
URL:https://bme.utoronto.ca/event/targeting-tumor-extracellular-matrix-for-precision-cancer-imaging-and-therapy/
LOCATION:Princess Margaret Cancer Centre\, 610 University Ave\, 6th floor\, Bob Bell Auditorium
CATEGORIES:External Speaker Series
END:VEVENT
END:VCALENDAR