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DTSTART;TZID=America/Toronto:20220913T120000
DTEND;TZID=America/Toronto:20220913T130000
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UID:37597-1663070400-1663074000@bme.utoronto.ca
SUMMARY:Invited Academic Seminar Series – Ehsan Hoque- Embedding human values in digital medicine (Hybrid Delivery)
DESCRIPTION:Speaker\nEhsan Hoque\nAssociate Professor\nComputer Science\nUniversity of Rochester \n\nAbstract\nMany argue that making interoperability\, federal incentives\, barcoding\, and deep learning is the core of revolutionizing healthcare information technology. It is. But it is also about developing technologies that align with our values and integrate effortlessly with our lifestyles and healthcare workflow while improving access and equity. \nIn this talk\, I will highlight the following projects and their design principles\, technical contributions\, and a roadmap to integrating them within the existing healthcare workflow. \n1)      How to develop an automated screening and tracking of Parkinson’s disease—the fastest-growing neurological disability —through a series of tasks on a webcam anytime\, anywhere? \n2)      How can AI assist doctors in improving empathy and listening skills as they help terminally ill patients make critical decisions? \n3)      How can virtual avatars with standardized\, repeatable\, and objective feedback improve the social skills of individuals who struggle with socio-emotional communication\, such as those with Autism? \nAlong with technical contributions\, I will reflect on the journey of how a trained computer scientist like myself could get into healthcare research driven by personal circumstances and enabled by excellent collaborators. \nBio: Ehsan Hoque is an associate professor of computer science at the University of Rochester\, where he co-leads the Rochester Human-Computer Interaction (ROC HCI) Group. From 2018-2019\, he was also the Interim Director of the Goergen Institute for Data Science. Ehsan earned his Ph.D. from MIT in 2013\, where the MIT Museum highlighted his dissertation—the development of an intelligent agent to improve human ability — as one of MIT’s most unconventional inventions. Building on the work/patent\, Microsoft released “Speaker Coach” available in PowerPoint. Ehsan is best known for introducing and extensively validating the idea of using AI to train and enhance elements of basic human ability. \nEhsan and his students’ work has been recognized by NSF CAREER Award\, MIT TR35\, Young Investigator Award by the US Army Research Office (ARO). In 2017\, Science News named him one of the 10 scientists to watch\, and in 2020\, the National Academy of Medicine recognized him as one of the emerging leaders in health and medicine. Ehsan is blessed to be the primary caregiver of his younger brother\, 22\, who is nonverbal and diagnosed with Autism and down syndrome. \n\nHost\nLueder Kahrs
URL:https://bme.utoronto.ca/event/invited-academic-seminar-series-ehsan-hoque/
LOCATION:MS3153
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2022/06/Hoque-Ehsan-Nov-2021-LR.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220914T120000
DTEND;TZID=America/Toronto:20220914T130000
DTSTAMP:20260524T085830
CREATED:20220909T192346Z
LAST-MODIFIED:20220913T193731Z
UID:38147-1663156800-1663160400@bme.utoronto.ca
SUMMARY:Careers Beyond Academia - Laura Smith\, PhD Principal Scientist\, AmacaThera and Stephanie Fisher\, PhD Senior Scientist\, BlueRock Therapeutics
DESCRIPTION:About the series\nTo what extent can we plan and design our careers? How much depends on our environment\, the choices we make\, the opportunities that present themselves\, the networks we build\, and the achievements and failures we experience along the way? Medicine by Design and Stem Cell Network have partnered to host Careers Beyond Academia\, a virtual career seminar series that will profile a wide variety of different careers available to trainees who hold a degree in the life sciences. The goal of the series is to help trainees understand the different careers available outside of academia\, the skills required for certain positions\, and some of the daily functions of those positions.\nVirtual Event – Register Here\nSpeakers:\nLaura Smith\, PhDPrincipal Scientist\, AmacaThera\nStephanie Fisher\, PhDSenior Scientist\, BlueRock Therapeutics\nEach session will feature two speaker presentations that will be recorded and available on both Medicine by Design and Stem Cell Network’s website and YouTube channel. Trainees will be able to participate in a joint Q&A and panel discussion during the session.\n 
URL:https://bme.utoronto.ca/event/careers-beyond-academia-laura-smith-phd-principal-scientist-amacathera-and-stephanie-fisher-phd-senior-scientist-bluerock-therapeutics/
LOCATION:Virtual
CATEGORIES:External Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220915T120000
DTEND;TZID=America/Toronto:20220915T123000
DTSTAMP:20260524T085830
CREATED:20220824T165250Z
LAST-MODIFIED:20220914T210730Z
UID:38483-1663243200-1663245000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Aaron Rosenstein
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Recording cellular histories in DNA with prime editing\nAbstract: Recording cellular stimuli into DNA has been a common aspiration of synthetic biologists for the purposes as both a research tool and eventual clinical diagnostic application. Whether as a means of understanding interactions on the single-cell level\, or reconstructing histories of cellular events\, a cellular DNA recording device has widespread utility. Previous attempts at building a robust recorder\, however\, have fallen short on this goal. Here I present steps taken towards developing a recording device which can incorporate sequential analog signals of events into genomic DNA. This device will leverage prime editing as a means of integrating signals encoded on prime editing guide RNAs (pegRNAs) into a specific region of the genome termed recording loci\, while pegRNA expression will be induced by the magnitude of signals respectively. I envisage a mechanism whereby repeated prime editing can construct an organized cellular record of event histories. Development of this device requires empirical identification of the sequence-determinants of effective prime editing\, as well as constructs for translation of diverse cellular signals into pegRNA messages of commensurate magnitude. Preliminary results indicate a baseline for recording synthetic signals in this manner. Ultimately this project will yield a robust recording device which can meet investigator’s needs\, and can hopefully be adopted as both a research tool and clinical diagnostic device.\nSupervisor Name: Dr. Michael Garton\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-aaron-rosenstein/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220916T123000
DTEND;TZID=America/Toronto:20220916T130000
DTSTAMP:20260524T085830
CREATED:20220824T165250Z
LAST-MODIFIED:20220915T212307Z
UID:38484-1663331400-1663333200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Mohamed Elsayed
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Towards automated cell isolation using Optoelectronic Tweezers and Digital Microfluidics\nAbstract:\nOptoelectronic tweezers uses patterned illumination to generate electric field gradients\, inducing dielectrophoretic forces that can move objects.\nI will introduce light-driven micromotors and micromachines based on optoelectronic tweezers. Using a circular micro-gear as a unit component\, we demonstrate a range of new functionalities\, including a touchless micro- feed-roller that allows the programming of precise three-dimensional particle trajectories\, multi-component micro-gear trains that serve as torque- or velocity-amplifiers\, and micro- rack-and-pinion systems that serve as microfluidic valves.\nI will present the utility of this technique in a biological application through a project “Autonomous control of optoelectronic microrobots for brain stem cell isolation”. There are various exciting research questions in the field of neuroscience that require harvesting stem cells from mouse brains. Current methods for harvesting stem cells have poor yield and often require pooling cells from various mice\, placing serious limitations on the type of research. We explored using the optoelectronic micro-robot to harvest stem cells from primary dissection cell suspensions. These are sensitive cells so they benefit strongly from the gentle approach offered by the optoelectronic micro-robot.\nI will then switch gears to present work done to date in another project using digital microfluidics “Automated processing of sexual assault samples to enable rapid DNA analysis”. Sexual assault samples contain DNA from multiple sources\, making them one of the most challenging types of forensic samples to analyze\, often beyond the reach of rapid DNA analyzers. The goal of this project is to develop a workflow that facilitates the use of rapid DNA typing instruments for sexual assault samples.\nSupervisor Name: Aaron Wheeler\nYear of Study: 5\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-mohamed-elsayed/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220920T120000
DTEND;TZID=America/Toronto:20220920T130000
DTSTAMP:20260524T085830
CREATED:20220704T182645Z
LAST-MODIFIED:20220919T195231Z
UID:37912-1663675200-1663678800@bme.utoronto.ca
SUMMARY:Global Speaker Series: Gordon Fishell\, PhD – Harvard University
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. Medicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Gordon Fishell\, PhD\, Professor of Neurobiology\, Harvard Medical School and the Stanley Center at the Broad. The title of this talk will be\, “The intimate dependence and remarkable precision of cortical interneurons.” In Person – Register Here\nVirtual – Register Here\nHybrid event\, with in-person and virtual options\nIn-person will be held at the Terrence Donnelly Centre for Cellular & Biomolecular Research\, Red Room.\nVirtual event links will be sent after registration.\nMore About gordon fishell:\nProfessor Fishell teaches in the department of Neurobiology at Harvard Medical center and is an institute member of the Broad institute. He was previously the associate director of the New York University (NYU) Neuroscience Institute\, Julius Raines Professor of Neuroscience and Physiology at NYU\, and director of the graduate program in neuroscience and physiology at the NYU School of Medicine. Professor Fishell completed his Ph.D. in neurobiology from the University of Toronto and conducted postdoctoral research at Columbia University and the Rockefeller University. His laboratory is interested in how the architecture of brain circuits are assembled\, with a special focus on the diverse populations of inhibitory interneurons that are found in both pallial and subpallial telencephalon. Professor Fishell’s laboratory has spent the past 20 years working to understand the inhibitory cells that regulate excitatory signaling in the brain.\n Learn more about Gordon Fishell
URL:https://bme.utoronto.ca/event/global-speaker-series-gordon-fishell-phd-harvard-university/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:External Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220921T120000
DTEND;TZID=America/Toronto:20220921T123000
DTSTAMP:20260524T085830
CREATED:20220906T175315Z
LAST-MODIFIED:20220920T213744Z
UID:38664-1663761600-1663763400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Runjie (Bill) Shi
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Next Generation Visual Field Testing\nAbstract: The visual field test (also known as perimetry) is a psychophysical test to test the light sensitivity across a grid of locations in a patient’s visual field. It is an indispensable tool for ophthalmologists to diagnose and monitor eye diseases\, such as glaucoma. Current perimetry machines (“perimeters”) are big\, expensive\, and require trained technicians to operate. Current algorithms take a long time (3-5 minutes) to perform each eye’s test. In this talk I will briefly describe our efforts on modernizing the visual field test. On the hardware front\, we are making the test portable and inexpensive by adapting the test to a portable VR platform. On the software front\, we are incorporating data-driven algorithms to reconstruct the visual field at test time using fewer trials. Lastly I will describe how these advances allow for unprecedented novel applications of the visual field test\, such as in mobile clinics in low-resource settings.\nSupervisor Name: Willy Wong\nYear of Study: 3\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-runjie-bill-shi/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220921T123000
DTEND;TZID=America/Toronto:20220921T130000
DTSTAMP:20260524T085830
CREATED:20220907T175245Z
LAST-MODIFIED:20220907T175245Z
UID:38679-1663763400-1663765200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Azadeh Assadi
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Applying clinician macrocognition in designing decision support\nAbstract:\nIntroduction: Compared to children without congenital heart disease (CHD)\, those with CHD\nexperience a significantly higher hospital admission\, morbidity\, and mortality associated with\ntheir acute presentation to the emergency department (ED). The burden of residual lesions and\nthe natural history of many CHDs predisposes these children to hemodynamic fragility with\ncommon childhood illnesses and altered response to traditional resuscitative measures. Their\noptimal outcome requires CHD-expertise which is limited in local EDs. Hence\, there is an urgent\nneed for a sociotechnological solution to support the management of these patients in the ED. In\nthis study\, a CHD-specific clinical decision support system (CDSS) is developed and evaluated\nbased on CHD-experts and ED physicians’ macrocognition.\nMethods: Using the critical decision method\, a cognitive task analysis (CTA) of CHD-experts\nand ED physicians was conducted to understand their macrocognitive differences when\nmanaging acutely ill pediatric CHD patients. Framework analysis was then used to identify key\ndecision requirements and design concepts to design the prototype CDSS using decision centered\ndesign. Heuristic and usability testing was completed on versions of the proposed CDSS while the effect of the CDSS on ED physicians’ decision making was tested using a scenario-based\nsimulation study.\nResults: The most pertinent differences in decision making between CHD-experts and ED\nphysicians were in sensemaking\, anticipation\, and managing complexity. Accordingly\, the key\ndecision requirements and design concepts incorporated into the prototype CDSS involved\nappreciating the CHD physiology\, identifying CHD-specific diagnoses\, and selecting\nappropriate CHD interventions. Use of the CDSS significantly improved ED physicians’ CHDspecific decision-making (M= 5.43\, 95%CI 3.7-7.2).\nConclusion: This study reveals differences in CHD-expert and ED physicians’ macrocognition\nand decision making while also proposing a design approach to develop and evaluate a CHDspecific CDSS. These findings can be used to design other sociotechnological solutions to\nsupport the care of pediatric CHD patients.\nSupervisor Name: Patricia Trbovich\nYear of Study: 5\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-azadeh-assadi-2/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220921T123000
DTEND;TZID=America/Toronto:20220921T130000
DTSTAMP:20260524T085830
CREATED:20220907T175245Z
LAST-MODIFIED:20220920T213744Z
UID:38678-1663763400-1663765200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Azadeh Assadi
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Applying clinician macrocognition in designing decision support\nAbstract:\nIntroduction: Compared to children without congenital heart disease (CHD)\, those with CHD\nexperience a significantly higher hospital admission\, morbidity\, and mortality associated with\ntheir acute presentation to the emergency department (ED). The burden of residual lesions and\nthe natural history of many CHDs predisposes these children to hemodynamic fragility with\ncommon childhood illnesses and altered response to traditional resuscitative measures. Their\noptimal outcome requires CHD-expertise which is limited in local EDs. Hence\, there is an urgent\nneed for a sociotechnological solution to support the management of these patients in the ED. In\nthis study\, a CHD-specific clinical decision support system (CDSS) is developed and evaluated\nbased on CHD-experts and ED physicians’ macrocognition.\nMethods: Using the critical decision method\, a cognitive task analysis (CTA) of CHD-experts\nand ED physicians was conducted to understand their macrocognitive differences when\nmanaging acutely ill pediatric CHD patients. Framework analysis was then used to identify key\ndecision requirements and design concepts to design the prototype CDSS using decision centered\ndesign. Heuristic and usability testing was completed on versions of the proposed CDSS while the effect of the CDSS on ED physicians’ decision making was tested using a scenario-based\nsimulation study.\nResults: The most pertinent differences in decision making between CHD-experts and ED\nphysicians were in sensemaking\, anticipation\, and managing complexity. Accordingly\, the key\ndecision requirements and design concepts incorporated into the prototype CDSS involved\nappreciating the CHD physiology\, identifying CHD-specific diagnoses\, and selecting\nappropriate CHD interventions. Use of the CDSS significantly improved ED physicians’ CHDspecific decision-making (M= 5.43\, 95%CI 3.7-7.2).\nConclusion: This study reveals differences in CHD-expert and ED physicians’ macrocognition\nand decision making while also proposing a design approach to develop and evaluate a CHDspecific CDSS. These findings can be used to design other sociotechnological solutions to\nsupport the care of pediatric CHD patients.\nSupervisor Name: Patricia Trbovich\nYear of Study: 5\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-azadeh-assadi/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220923T120000
DTEND;TZID=America/Toronto:20220923T123000
DTSTAMP:20260524T085830
CREATED:20220903T173742Z
LAST-MODIFIED:20220922T213737Z
UID:38643-1663934400-1663936200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Thaisa Luup Kannen
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Multi-axes electromagnetic sample handler for live imaging of organoids structure and dynamics\nAbstract:\nOrganoids are a flexible experimental model to explore countless human conditions. They can emulate essential specific functions of an in vivo system in physiological and pathological conditions. Acquiring three-dimensional (3D) volumetric images is critical while challenging in many live organoid-based studies due to these sample structures. Non-idealities worsen as more profound images are acquired. Furthermore\, there are unavoidable distortions from the imaging system. Current methods to decrease these issues are often expensive\, highly complex\, limited to specific usage\, or unsuitable for live organoid experiments.\nBy increasing the samples’ freedom of movement within the microscope field of view for imaging samples at different angles\, these non-idealities can be minimized. We are developing a spherical-shaped electromagnetic sample handler to provide a multi-axis rotational imaging system. The sample handler has evenly distributed electromagnets individually controlled by an open-loop micro-stepping control system. It controls the electromagnetic sample handler over samples’ x-y-z-theta space. Methods were developed to measure the sample handler quality\, rotation precision\, handling\, and imaging stability.\nAn image reconstruction methodology is coded to minimize light penetration limitations\, and the same will be made for the point spread function distortion in the z axis. An optimization algorithm will select the optimum angle\, which better shows the organoid structure and dynamics. The algorithm will use images from different angles to build the reconstructed image\, reducing non-idealities for thicker live organoids. The algorithm’s validation will be made with a nano printed sample.\nImage acquisition through this device will better represent biological specimens and promote more precise quantitative microscopy analyses. It can improve the quality of live 3D organoid images by optimizing angular positioning during imaging acquisition\, reducing non-idealities and working distance limitations. It is a cost-effective\, robust\, and user-friendly tool\, and it will open new possibilities for organoid research.\nSupervisor Name: Christopher Yip\nYear of Study: 3\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-thaisa-luup-kannen/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220927T110000
DTEND;TZID=America/Toronto:20220927T120000
DTSTAMP:20260524T085830
CREATED:20220907T140311Z
LAST-MODIFIED:20220907T140311Z
UID:38674-1664276400-1664280000@bme.utoronto.ca
SUMMARY:TBEP Research Seminar: Wnt in heart formation and regeneration
DESCRIPTION:Daniela Panáková\, Ph.D. \nGroup Leader \nMax Delbrück Center\, Berlin\, Germany \nDaniela Panáková received her PhD in 2005 at Max Planck Institute of Molecular Cell Biology and Genetics\, Dresden\, Germany under the supervision of Suzanne Eaton. She has worked with Drosophila model on the concept of how the hydrophobic morphogens such as Wnt can spread in tissues over long distances\, and identified a novel mechanism whereby lipoprotein particles act as vehicles for the lipid-linked proteins\, and are required for Wingless and Hedgehog signaling. In 2007\, as a Human Frontier Science Program Long-term Fellow she moved to Harvard Medical School/Brigham & Women’s Hospital\, Boston\, MA to work with Calum MacRae. Using zebrafish\, she has demonstrated non-canonical Wnt signaling modulates electrical coupling in the developing heart through negative regulation of L-type Ca2+ channel function\, which established a novel limb in non-canonical Wnt signaling. She was awarded highly esteemed Helmholtz Young Investigator Award to start her own research lab at Max Delbrück Center in Berlin\, Germany in 2011. Teaching\, training and mentoring form a great part of her endeavors as an independent investigator. She has served as a Confidential Advisor for both the PhD and Postdoc body at the MDC and was part of the Gender Equality and Equal Opportunity team at the MDC. \nDaniela Panáková’s long-standing research interest addresses how developmental signaling and physiology regulate cellular responses including cell fate and differentiation. Her main focus is to decipher how Wnt pathway interacts with mechanical and electrical cues in cell and zebrafish models. Her group made significant contributions to the understanding of heart formation and function\, and more recently also to heart regeneration. Her ultimate goal is to uncover cellular mechanisms underlying cardiovascular diseases including heart failure. Her research focuses on cardiac biology\, but on the broader scale has implication for cell\, tissue and organ biology.
URL:https://bme.utoronto.ca/event/tbep-research-seminar-wnt-in-heart-formation-and-regeneration/
CATEGORIES:External Speaker Series
ORGANIZER;CN="Translational Biology and Engineering Program (TBEP)":MAILTO:reception.tbep@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220929T120000
DTEND;TZID=America/Toronto:20220929T123000
DTSTAMP:20260524T085830
CREATED:20220912T210236Z
LAST-MODIFIED:20220927T161624Z
UID:38757-1664452800-1664454600@bme.utoronto.ca
SUMMARY:Research: From academia to venture capital (In-person Guest Lecture)
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream \n*Note this lecture can count towards your seminar series requirement  \nPresentation Title: Research: From academia to venture capital \nLocation:  WB116 \nAbstract: \nAs scientists\, we continuously strive to push our understanding of the world. As scientists in venture capital\, we try to apply the learnings from academic research to help identify\, evaluate\, and build novel companies. Join us for a discussion on the mission and philosophy of the Research team at Foresite Capital\, and the similarities and differences between research in academia and venture. \nLecturers: \nScott McIsaac\, PhD \nScott is a scientist and technologist\, having made numerous contributions in the fields of synthetic biology\, systems biology\, and the computational and experimental study of transcriptional regulation. Scott comes to Foresite from Calico (a Google/Alphabet-funded life sciences company)\, where he led an independent research laboratory as one of its earliest hires. Scott received his Ph.D. from Princeton University with David Botstein and his postdoctoral training at CalTech with Frances Arnold. \nJacob Barlow\, PhD \nJacob has a broad range of academic and industry research experience in sequencing technologies\, drug delivery\, diagnostics\, and the human microbiome. Previously\, Jacob was a fellow at Northpond Ventures handling life science tools and diagnostics investments and completed his Ph.D. in Bioengineering from CalTech in the lab of Rustem Ismagilov. He also worked on RNA delivery at Moderna Tx and oral peptide delivery at Entrega Tx. \n 
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-ivy-hon/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220929T120000
DTEND;TZID=America/Toronto:20220929T123000
DTSTAMP:20260524T085830
CREATED:20220912T210236Z
LAST-MODIFIED:20220928T213730Z
UID:38758-1664452800-1664454600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Ivy Hon
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Guest Lecture: TBA\nAbstract: TBD\nSupervisor Name: N/A\nYear of Study: N/A\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-ivy-hon-2/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220930T120000
DTEND;TZID=America/Toronto:20220930T123000
DTSTAMP:20260524T085830
CREATED:20220824T165250Z
LAST-MODIFIED:20220929T213734Z
UID:38485-1664539200-1664541000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Julien Couture-Senécal
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Optimization of ionizable lipids for mRNA delivery\nAbstract: Lipid nanoparticles (LNPs) play a key role in the efficacy of mRNA vaccines. Efforts have focused on engineering the ionizable lipid component as it has dramatic effects on safety and efficacy. In this work\, we’ve designed a new ionizable lipid optimized for intramuscular administration of mRNA. We also provided insights on the effect of molecular design and nanoparticle physicochemical parameters on mRNA delivery efficiency.\nSupervisor Name: Omar F. Khan\nYear of Study: 3\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-julien-couture-senecal/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220930T123000
DTEND;TZID=America/Toronto:20220930T130000
DTSTAMP:20260524T085830
CREATED:20220829T170743Z
LAST-MODIFIED:20220929T213734Z
UID:38571-1664541000-1664542800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Chris Lee
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: De Novo Design of Novel Peptide Structure\nAbstract: 164 College Street\nSupervisor Name: Michael Garton\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-chris-lee/
CATEGORIES:Graduate Seminar Series
END:VEVENT
END:VCALENDAR