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CREATED:20230509T151030Z
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UID:41558-1686319200-1686322800@bme.utoronto.ca
SUMMARY:Plasmon-enhanced Fluorescence Induced Stimulated Raman Scattering as Non-destructive Non-linear Optical Method in Nanobiosensing and Bioimaging
DESCRIPTION:Mohammad E. Khosroshahi\nNanobiophotonics & Biomedical Research Laboratory\, MIS-Electronics Inc.\, \nRichmond Hill\, Canada \n  \nAbstract \nThis work describes the generation and observation of multi-wavelengths due to stimulated Raman scattering (SRS) from deep red to near-infrared (NIR) induced by plasmon-enhanced fluorescence (PEF) of fluorescein isothiocyanate (FITC) conjugated gold nanoparticles (F-AuNP). The plasmonic solution was excited by a 488 nm diode laser and the PEF due to overlapping of FITC\, and localized surface plasmon resonance (LSPR) of AuNP resonance peaks provided an efficient coupling between the near-field of LSPR of AuNPs as a nano-antenna and the molecules followed by an enhanced emission. Resonance Rayleigh scattering and PEF conditions are both satisfied. PEF acts as Stokes radiation and secondary pump beam for further optical excitation within the medium. Longer wavelengths with higher output power and shorter wavelengths with lower are detected at varying angles. Time-resolved PEF spectroscopy revealed the effect of enhanced emission followed by its quenching. In addition\, F-AuNPs were incubated and taken up by the king oyster mushroom (KOM) grown in the lab studied by phase contrast microscope (PCM) and fluorescence microscope (FM). The results showed PEF and SRS visible colors within the mycelium hyphae. Therefore\, it is concluded that non-linear optical mechanisms can be utilized for non-destructive biomedical applications such as invitro and in vivo contrast-enhanced fluorescence sensing and nano-bioimaging of cells and tissues as monitoring techniques. \nBiography \nProfessor Mohammad E. Khosroshahi received his Ph.D. in Applied Physics (Application of Lasers in Medicine) from Hull University (UK) in 1993 with the thesis on ophthalmological tissue ablation with tunable mid-IR and excimer lasers in collaboration with Moorefields hospital in London. He joined the Biomaterial and Tissue Engineering group of the Faculty of Biomedical Engineering at Amirkabir University of Technology (AUT) in Tehran where he was a Full Professor. He has been the Director of AUT Laser and Optics Research Center\, Associate Dean of Research\, and Chair of Biomaterial Group. In 2013\, he joined the University of Toronto\, Department of Mechanical & Industrial Engineering (MIE) as a Visiting Professor working on ‘’Contrast-enhanced photoacoustic imaging of Tumor’’ at the Center for Advanced Diffusion-Wave and Photoacoustic Technologies (CADIPT). He then continued as a research associate at CADIPT working on the contrast-enhanced imaging of blood and became the faculty adjunct Professor in 2018. \nProfessor Khosroshahi is the author of two books:  Laser Applications in Medicine\, and Applications of Biophotonics and Nanobiomaterials in Biomedical Engineering\, and co-author of two book chapters on Laser surface modification of titanium alloys as biomedical implants. He has published 110 peer-reviewed papers and has 2 patents and patent-pending related to nanobiosensors. His main research interests are Nanobiophotonics\, Nanomedicine\, Multifunction nanostructures\, Targeted drug delivery\, Targeted photothermal therapy\, Guided bioimaging\, biological chaos\, Cancer thermodynamics\, Optical detection of dental decay\, Photoacoustic and Photothermal characterization. Currently\, Professor Khosroshahi is Director of the Nanobiophotonics and Biomedical Research Lab at MIS-Electronics in Richmond Hill where he is working on the development of novel colloidal and substrate nanobiosensors based on the Plasmon-enhanced fluorescence spectroscopy (PEFS) and Enhanced-surface-enhanced Raman scattering (E-SERS) for targeted detection of breast cancer biomarkers such as HER-II and CA 15-3\, dual-mode guided bioimaging\, fluorescence microscopy\, and contrast phase microscopy. He is a member of the Editorial Board of the Journal of Nanomedicine and Nanotechnology\, a fellow member of the Institute of Nanotechnology\, a member of the Canadian Association of Physics\, Canadian Medical and Biological Engineering Society\, Optical Society of America\, and SPIE.
URL:https://bme.utoronto.ca/event/plasmon-enhanced-fluorescence-induced-stimulated-raman-scattering-as-non-destructive-non-linear-optical-method-in-nanobiosensing-and-bioimaging/
LOCATION:MC 331\, 5 King's College Rd\, Toronto\, ON\, M5S 3G8\, Canada
CATEGORIES:External Speaker Series
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DTSTART;TZID=America/Toronto:20230620T110000
DTEND;TZID=America/Toronto:20230620T120000
DTSTAMP:20260414T160813
CREATED:20230607T141938Z
LAST-MODIFIED:20230607T141938Z
UID:41736-1687258800-1687262400@bme.utoronto.ca
SUMMARY:The Journey from Concept to Commercial
DESCRIPTION:  \nPlease join us for an ECHO webinar featuring Garrett Schwab\, who will provide an overview of his vast experience developing and commercializing novel therapeutic medical technologies. \nXII Medical is a privately held medical technology company developing a novel neurostimulation system designed to improve patient experience and outcomes for the millions suffering from Obstructive Sleep Apnea. \nGuest Speaker\nGarrett Schwab\, BA\, MBA \nPresident and CEO\, XII Medical \nRegister in advance for this webinar. After registering\, you will receive a confirmation email containing information about joining the webinar.\nECHO is an entrepreneurship training program\, funded and organized in a partnership between (i) the Translational Biology and Engineering Program (TBEP)\, the University of Toronto component of the Ted Rogers Centre for Heart Research\, and (ii) the Health Innovation Hub (H2i). For more information\, visit: https://tedrogersresearch.ca/echo/
URL:https://bme.utoronto.ca/event/the-journey-from-concept-to-commercial/
LOCATION:ON
CATEGORIES:Events & Workshops
ORGANIZER;CN="Translational Biology and Engineering Program (TBEP)":MAILTO:reception.tbep@utoronto.ca
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DTSTART;TZID=America/Toronto:20230620T120000
DTEND;TZID=America/Toronto:20230620T130000
DTSTAMP:20260414T160813
CREATED:20230615T195640Z
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UID:41782-1687262400-1687266000@bme.utoronto.ca
SUMMARY:Enlightening Panel discussion: Navigating the Path to a Professorship Position
DESCRIPTION:Time: June 20th\, 12-1PM \nLocation: KITE\, UC Lecture theatre (basement) \n  \nAre you concerned how to secure a job in academia\, post-COVID? \nWe have four outstanding panelists who will start their career as Assistant Professors this fall. Please join us at a vibrant event\, co-sponsored by IEEE-EMBS Toronto and FIBRE\, to hear from our panelist and ask your questions. \nAnd\, there will be pizza too 😊 \nTo facilitate logistics of the event\, please kindly register at:   https://events.vtools.ieee.org/m/363572 \nIf you have any questions\, please feel free to reach out to Ivana Culjak at Ivana.Culjak@uhn.ca
URL:https://bme.utoronto.ca/event/enlightening-panel-discussion-navigating-the-path-to-a-professorship-position/
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