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X-WR-CALDESC:Events for Institute of Biomedical Engineering (BME)
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DTSTART;TZID=America/Toronto:20230810T103000
DTEND;TZID=America/Toronto:20230810T113000
DTSTAMP:20230808T182856Z
CREATED:20230808T182726Z
LAST-MODIFIED:20230808T182856Z
UID:42150-1691663400-1691667000@bme.utoronto.ca
SUMMARY:Tiny Bubbles: New Applications of Nanoscale Contrast Media in Ultrasound-based Cancer Diagnosis and Therapy
DESCRIPTION:Princess Margaret Special Seminar presents: \n  \nAGATA EXNER\, Ph.D\nHenry Willson Payne Professor & Vice Chair for Basic Research \nDepartment of Radiology \nCase Western Reserve University School of Medicine \nUniversity Hospitals of Cleveland\, Ohio \n  \nHost: Dr. Gang Zheng \nSponsored by Medical Biophysics\, University of Toronto
URL:https://bme.utoronto.ca/event/tiny-bubbles-new-applications-of-nanoscale-contrast-media-in-ultrasound-based-cancer-diagnosis-and-therapy/
LOCATION:Princess Margaret Cancer Research Tower (PMCRT) Room 4-204\, 101 College St\, 4th Floor\, Rm 4-204\, Toronto\, Ontario\, Canada
CATEGORIES:External Speaker Series
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DTSTART;TZID=America/Toronto:20230821T103000
DTEND;TZID=America/Toronto:20230821T113000
DTSTAMP:20230815T145518Z
CREATED:20230815T145518Z
LAST-MODIFIED:20230815T145518Z
UID:42192-1692613800-1692617400@bme.utoronto.ca
SUMMARY:Delivery of Biologics for Rotator Cuff Muscle Healing - Dr. Johnna Temenoff
DESCRIPTION:Speaker\nDr. Johnna Temenoff\, PhD Georgia Tech/Emory University \nAbstract\nAfter rotator cuff tendon tear\, marked degeneration of the attached muscle is apparent clinically\, with both fibrous and fatty infiltration of the tissue. Our laboratory is working on delivery strategies for biologics\, including proteins and cells\, that might slow or reverse this degeneration. In particular\, our laboratory has focused on “jump-starting” host regenerative processes through use of glycosaminoglycan (GAG)-based biomaterials for release of cytokines to promote the recruitment of pro-healing cell populations\, such as pro- resolving macrophages\, and mesenchymal stromal cells (MSCs)\, into the muscle. In other work\, we have explored priming strategies for MSCs to alter their immunomodulatory properties as a means to reduce inflammation\, such as that which occurs in muscle after rotator cuff tendon tear. \nBiography\nDr. Johnna S. Temenoff is the Carol Ann and David D. Flanagan Professor the Coulter Department of Biomedical Engineering at Georgia Tech/Emory University. She is also currently the Deputy Director of a NSF Engineering Research Center in Cell Manufacturing Technologies (CMaT). Scientifically\, Dr. Temenoff is interested in tailoring the molecular interactions between glycosaminoglycans and proteins/cells for use in regenerative medicine applications. Her laboratory focuses primarily on promoting repair after injuries to the tissues of the shoulder\, including cartilage\, tendon\, and muscle. \nDr. Temenoff has been honored with several prestigious awards\, such as the NSF CAREER Award\, Arthritis Foundation Investigator Award and Society for Biomaterials (SFB) Clemson Award for Contributions to the Literature\, and was named to the College of Fellows of the American Institute for Medical and Biological Engineers (AIMBE)\, as a Fellow of the Biomedical Engineering Society (BMES) and as a Fellow of Biomaterials Science and Engineering\, International Union of Societies for Biomaterials Science and Engineering (IUSBSE). She has co-authored a highly successful introductory textbook – Biomaterials: The Intersection of Biology and Materials Science\, by J.S. Temenoff and A.G. Mikos (now in a 2nd edition)\, for which Dr. Temenoff and Dr. Mikos were awarded the American Society for Engineering Education’s Meriam/Wiley Distinguished Author Award for best new engineering textbook.
URL:https://bme.utoronto.ca/event/delivery-of-biologics-for-rotator-cuff-muscle-healing-dr-johnna-temenoff/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:External Speaker Series
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DTSTART;TZID=America/Toronto:20230821T130000
DTEND;TZID=America/Toronto:20230821T133000
DTSTAMP:20230818T132252Z
CREATED:20230816T163634Z
LAST-MODIFIED:20230818T132252Z
UID:42205-1692622800-1692624600@bme.utoronto.ca
SUMMARY:Mon Aug 21st – Carter Teal’s Public Seminar
DESCRIPTION:Dear BME community:  \nFor anyone interested\, Carter Teal will be having their public seminar on August 21st @ 1:00PM in the Red Room at the Donnley center. Anyone interested in attending please see details below.  \nPublic Seminar: “Affinity-Based Approaches for Controlling Release of Therapeutic Proteins from Biopolymer Hydrogels”\nName: Carter Teal\nExam Date: August 21\, 2023\nTime: 1:00PM\nLocation: Red Seminar Room in the Donnley (160 College Street).\nAbstract: Carter Teal – PhD Thesis Abstract_\nPulic Seminar Link: Join Zoom Meeting\nhttps://utoronto.zoom.us/j/86965840489 \nMeeting ID: 869 6584 0489\nPasscode: 593511
URL:https://bme.utoronto.ca/event/mon-aug-21st-carter-teals-public-seminar/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:Graduate Seminar Series
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DTSTART;TZID=America/Toronto:20230823T100000
DTEND;TZID=America/Toronto:20230823T110000
DTSTAMP:20230815T145746Z
CREATED:20230815T145746Z
LAST-MODIFIED:20230815T145746Z
UID:42194-1692784800-1692788400@bme.utoronto.ca
SUMMARY:Immune Engineering: Detection and Treatment of Undesired Immune Responses - Dr. Johnna Temenoff
DESCRIPTION:Speaker\nDr. Lonnie Shea\, PhD University of Michigan \nAbstract\nVaccines are the initial immunotherapy by providing a means to activate an immune response to specific antigens to protect against disease. This success has motivated the development of alternative immunotherapies for treating undesired immune responses\, such as those found in autoimmune disease\, allergy\, organ transplantation\, and cancer\, with the objective to attenuate responses. For autoimmune and allergic disease\, we have developed nanoparticles loaded with antigen or allergen\, which suppresses the antigen specific response without impacting the remainder of the immune system. The nanoparticles maintain the antigen until internalization by immune cells\, with subsequent presentation of the antigen coincident with down-regulation of the co-stimulatory factors and up-regulation of negative co-stimulators. Similar nanoparticles have been applied to attenuate inflammation\, such as that associated with cancer progression. A critical need for treating undesired immune responses is the identification of disease prior to significant tissue damage\, with disease such as Type 1 Diabetes\, multiple sclerosis\, or metastatic cancer often detected through patients self- reporting symptoms. We have developed scaffold implants that support the formation of tissues that function as an immunological niche to represent the immune function in endogenous tissues. The early detection and treatment of undesired immune responses provides an opportunity to ameliorate disease while preserving tissue function. \nBiography\nLonnie Shea is the Steven A. Goldstein Collegiate Professor in the Department of Biomedical Engineering at the University of Michigan (U-M)\, which is joint between the College of Engineering and the School of Medicine. He received his PhD in chemical engineering and scientific computing from U-M in 1997\, working with Professor Jennifer Linderman. He then served as a postdoctoral fellow with then Chemical Engineering Professor David Mooney in the Department of Biologic and Materials Science at the U-M Dental School. \nShea was recruited to Northwestern University’s Department of Chemical and Biological Engineering and was on the faculty from 1999 to 2014. In 2014\, Shea returned to the University of Michigan as chair of the Department of Biomedical Engineering\, with his recruitment coinciding with the endowment of the chair position by William and Valerie Hall. His term as chair completed on June 30\, 2021. He is the Steven A. Goldstein Collegiate Professor of Biomedical Engineering and is an internationally recognized researcher at the interface of regenerative medicine\, drug and gene delivery\, and immune-engineering\, whose focus is on preventing tissue degeneration or promoting tissue regeneration. His projects include islet transplantation for diabetes therapies\, nerve regeneration for treating paralysis\, and diagnostics for immune dysfunction in cancer and autoimmunity. He is currently PI or co-PI on multiple NIH grants. \nShea has published more than 270 manuscripts. He served as director of Northwestern’s NIH Biotechnology Training Grant. He has received the Clemson Award from the Society for Biomaterials\, and also the recipient of their 2021 Technology Innovation and Development Award for his development of nanoparticles for tolerance in autoimmune disease. Shea is a fellow of the American Institute of Medical and Biological Engineering (AIMBE) and the Biomedical Engineering Society (BMES)\, a member of the editorial boards for multiple journals such as Molecular Therapy\, Biotechnology and Bioengineering\, and the Journal of Immunology and Regenerative Medicine.
URL:https://bme.utoronto.ca/event/immune-engineering-detection-and-treatment-of-undesired-immune-responses-dr-johnna-temenoff/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:External Speaker Series
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