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X-WR-CALDESC:Events for Institute of Biomedical Engineering (BME)
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DTSTART;TZID=America/Toronto:20230110T120000
DTEND;TZID=America/Toronto:20230110T130000
DTSTAMP:20230102T143723Z
CREATED:20220512T153024Z
LAST-MODIFIED:20230102T143723Z
UID:10000020-1673352000-1673355600@bme.utoronto.ca
SUMMARY:Invited Academic Seminar Series - Cynthia Reinhart-King - The Intersection of Mechanobiology and Cellular Metabolism in Cancer (Hybrid Delivery)
DESCRIPTION:Speaker\nCynthia Reinhart-King\nCornelius Vanderbilt Professor of Engineering\nProfessor of Biomedical Engineering\nDirector of Graduate Studies in Biomedical Engineering\nVanderbilt School of Engineering \n\nAbstract\nDuring solid tumor progression\, cells undergo mechanical and metabolic changes that help to fuel metastasis. To move\, cells must utilize ATP to fuel the the cellular contractility and forces that sustain migration\, however very little is known about how the metabolic state of a cell affects its ability to migrate and vice versa. In this talk\, I will describe my lab’s efforts to understand the forces driving cell movements in the tumor microenvironment and the energy required for movement. Combining tissue engineering approaches\, mouse models\, and patient samples\, we create and validate in vitro systems to understand how cells navigate the tumor stroma environment with the goal of identifying novel targets of cancer metastasis. Microfabrication and native biomaterials are used to build mimics of the paths created and taken by cells during metastasis. Using these platforms\, we have described a role for a balance between cellular energetics\, cell and matrix stiffness\, and confinement in determining migration behavior. Moreover\, we have extended this work into investigating the intersection of diabetes and the diabetic tissue microenvironment with tumor progression\, showing that mechanical changes in the tissue due to diabetes can promote cancer. Overall\, our work has demonstrated key mechanical drivers of metastasis within the tissue microenvironment. \n\nHost\nPenney Gilbert
URL:https://bme.utoronto.ca/event/invited-academic-seminar-series-cynthia-reinhart-king/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2022/05/Cynthia_Reinhart_King.jpg
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DTSTART;TZID=America/Toronto:20230111T120000
DTEND;TZID=America/Toronto:20230111T123000
DTSTAMP:20230110T202257Z
CREATED:20220921T213812Z
LAST-MODIFIED:20230110T202257Z
UID:10000121-1673438400-1673440200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Behrad TaghiBeyglou
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Development of accessible digital technologies to improve sleep assessment in people experiencing homelessness\nAbstract:\nIn Toronto\, there are 8\,700 people experiencing homelessness (PEH) on any given night. It has been shown that PEH are at high risk of chronic disorders\, such as diabetes\, heart or mental disease\, which are common comorbid conditions of sleep apnea. However\, there is no study on the prevalence and consequences of sleep apnea in PEH. Due to several barriers to healthcare\, such as low trust in care providers and difficulty visiting medical facilities\, PEH have limited access to sleep care. Hence\, sleep apnea remains a potential cause of morbidity and mortality in this population. The goal of this study is to assess the feasibility and potential of digital technologies to provide equitable access to sleep care for adults who live in shelters in Toronto.\nIn this study\, we aim to address the current gap in sleep care to shelter residents through 4 interconnected objectives. First\, we will investigate the prevalence of sleep problems among shelter residents. Second\, we will develop a smartphone application to estimate the risk of sleep problems using speech and video analyses during wakefulness\, to provide a more accessible and accurate tool to screen sleep disorders in PEH. Third\, in participants diagnosed with sleep apnea\, we will investigate the feasibility of providing patient-centered sleep apnea treatment\, including continuous positive airway pressure (CPAP) or oral appliances (OA). Fourth\, we will investigate the accuracy of a new approach based on snoring sounds analysis to predict the efficiency of OA to treat sleep apnea in PEH\, which would improve selection of the optimum treatment option for this population.\nBy accomplishing the objectives of this study\, more information about the sleep disorders in PEH will be gained\, and the feasibility of providing sleep apnea treatment in PEH will be investigated. Also\, with the help of digital technologies and simple modalities such as snoring sounds\, the diagnosis and treatment of sleep problems will be more feasible\, efficient\, and accessible for PEH.\nSupervisor Name: Dr. Azadeh Yadollahi\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-behrad-taghibeyglou/
CATEGORIES:Graduate Seminar Series
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BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230111T123000
DTEND;TZID=America/Toronto:20230111T130000
DTSTAMP:20230110T202257Z
CREATED:20221213T193756Z
LAST-MODIFIED:20230110T202257Z
UID:10000165-1673440200-1673442000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Ava Danialy
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Pre-clinical Evaluation of an Image-Guided High Intensity Focused Ultrasound Platform for in utero Therapy\nAbstract: N/A\nSupervisor Name: Dr. James Drake\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-ava-danialy/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230113T120000
DTEND;TZID=America/Toronto:20230113T123000
DTSTAMP:20230112T203736Z
CREATED:20221117T205248Z
LAST-MODIFIED:20230112T203736Z
UID:10000158-1673611200-1673613000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Sean McGrath
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Microbubbles for endobronchial ultrasound induced lung cancer diagnosis and therapy\nAbstract: TBD\nSupervisor Name: Naomi Matsuura\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-sean-mcgrath/
CATEGORIES:Graduate Seminar Series
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