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X-WR-CALNAME:Institute of Biomedical Engineering (BME)
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X-WR-CALDESC:Events for Institute of Biomedical Engineering (BME)
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DTSTART;TZID=America/Toronto:20230222T120000
DTEND;TZID=America/Toronto:20230222T123000
DTSTAMP:20230222T162232Z
CREATED:20230113T203749Z
LAST-MODIFIED:20230222T162232Z
UID:10000182-1677067200-1677069000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Aleksandra Dojnov
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Feasibility of non-invasively measuring neural activity evoked by saphenous nerve stimulation in humans\nAbstract: Rationale and Objectives. Overactive bladder (OAB) is a large problem\, affecting 14-18% of the population in Canada and the US. Saphenous nerve stimulation is an emerging therapy for treating OAB. Stimulation-evoked neural signals can produce the subjective perception of paresthesia\, but this does not confirm whether the neural target has been sufficiently activated and may be difficult in patients with impaired sensory processing. An objective measurement of non-invasive nerve stimulation could provide a more accurate representation of neural activation. Unfortunately\, since the saphenous nerve is a purely sensory nerve\, visible confirmation cannot be accomplished by measuring muscle contraction. This study investigated the feasibility of measuring evoked neural activity evoked as sensed by several cutaneous recording electrode configurations. Methodology. In 17 healthy volunteers (11 male; age = 24 ± 2.1 years\, range: 20-28; BMI = 22.5 ± 2.8)\, stimulation evoked neural activity was measured and analyzed for 4 recording configurations obtained using 5 electrodes located linearly on the top surface of the foot: monopolar\, bipolar\, tripolar\, and tetrapolar (see figure). Peak-to-peak amplitude (Vpp) was measured. Results. A high signal-to-noise ratio can be achieved by averaging the neural signals from a minimum of 70 pulses (i.e.\, 7 seconds at 10 Hz). Vpp at maximal recruitment ranged between 2-11 µV\, which is consistent with literature. Different stimulation thresholds follow patterns associated with stimulation-evoked physiological phenomena and reflect expected neural recruitment behaviour. The tetrapolar configuration yielded the largest Vpp. Conclusion and Significance. The results support the feasibility of using non-invasive recording electrodes to measure stimulation-evoked signals from the saphenous nerve. A tetrapolar configuration may provide the best recorded signal as it produces the greatest Vpp. Further work is needed to translate these initial findings into a clinical therapeutic device.\nSupervisor Name: Paul Yoo\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-aleksandra-dojnov/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230222T123000
DTEND;TZID=America/Toronto:20230222T130000
DTSTAMP:20230222T162233Z
CREATED:20221010T220747Z
LAST-MODIFIED:20230222T162233Z
UID:10000146-1677069000-1677070800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Vida Adeli Mosabbeb
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Vision-based gait assessment in older adults with dementia\nAbstract: Falls are a leading cause of morbidity and mortality in older adults with dementia residing in long-term care. Having access to a frequently updated and accurate estimate of short-term fall risk for each resident will enable care staff to provide targeted interventions to prevent falls and resulting injuries. To this end\, machine learning models to estimate and frequently update the short-term fall risk were trained on longitudinal data from 54 older adult participants with dementia. This study is the first to present a machine learning model capable of dynamically estimating short-term fall risk for older adults with dementia. The model used baseline fall risk scores\, gait measurements from baseline and in the past 6 days\, and daily dose of antipsychotic medication in the past 6 days.\nSupervisor Name: Babak Taati\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-vida-adeli-mosabbeb/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230223T120000
DTEND;TZID=America/Toronto:20230223T123000
DTSTAMP:20230223T162237Z
CREATED:20230124T210732Z
LAST-MODIFIED:20230223T162237Z
UID:10000188-1677153600-1677155400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Johnathan Lex
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Machine Learning to Predict and Optimize Arthroplasty Resource Utilization and Patient Outcomes\nAbstract:\nBackground\nThe gold-standard therapy for end-stage arthritis of the knee and hip is total knee and hip arthroplasty (TKA and THA\, respectively). They are the most common orthopaedic procedures carried out in the US\, with over 1.3 million of these operations performed in 2018\, a 21.9% increase from 2008. Global ageing and the continued obesity epidemic will cause this figure to continue to rise. Inefficiencies in surgical services are a major cause of Canadian healthcare’s growing costs and wait times. OR scheduling is a critical consideration in surgical care delivery with direct impacts on staffing and inventory planning across multiple hospital units (post- operative care units\, inpatient wards\, intensive care units). Manual scheduling requires that the human planner simultaneously reason about unknowns such as case-specific length-of-surgery\, hard constraints on the total amount of available OR time\, surgeon availability and caseload\, and soft constraints such as patient wait times\, case priorities\, and post-operative quality of life improvement\, all while maximizing throughput.\nSpecific Aims\n1. To evaluate neural network prediction models incorporating patient and operational factors for the prediction of duration of surgery and length of stay for primary and revision TKA/THA.\n2. To compare the impact of a two-stage machine learning and optimization approach on operating room efficiency compared to using historic scheduling practices (surgeon- estimated DOS)\, mean DOS\, mean surgeon-specific DOS and rolling mean surgeon- specific DOS.\n3. Determine if neural networks with patient\, surgeon and implant features can accurately predict improvement in patient reported outcome measures following TKA/THA.\nSupervisor Name: Dr. Cari Whyne\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-johnathan-lex/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230223T123000
DTEND;TZID=America/Toronto:20230223T130000
DTSTAMP:20230223T162237Z
CREATED:20221004T213737Z
LAST-MODIFIED:20230223T162237Z
UID:10000140-1677155400-1677157200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Ryan Yee
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Sara Vasconcelos\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-ryan-yee/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230224T120000
DTEND;TZID=America/Toronto:20230224T123000
DTSTAMP:20230224T162229Z
CREATED:20230209T212231Z
LAST-MODIFIED:20230224T162229Z
UID:10000194-1677240000-1677241800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Brendan Samaroo
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: An Adaptable Permeable Tissue Mimicking Phantom for Realistic Tumor Representation\, Calibration\, and Validation in DCE imaging\nAbstract:\nThe concept of dynamic contrast enhanced (DCE) imaging in combination with pharmacokinetic modeling of contrast agents (CA) is becoming an important tool in assessing a given tissue’s response to targeted interventions and the efficacy of drug delivery mechanisms . To calibrate DCE imaging and validate tracer pharmacokinetics\, such as perfusion\, vascular permeability\, diffusion and convection\, 3D structures known as phantoms are required to replace the need for tumors\, providing a simplified and controlled test environment . There are two main caveats with contemporary phantoms\, 1) they do not precisely represent the tumor microenvironment and microvasculature and 2) phantoms are constructed with non-tissue mimicking materials . Based on this\, the goal of this project is to improve on phantom design and validate its imaging functionality using tracers of varying molecular weights\, expanding upon traditional proof-of-concept methods.\nIt is hypothesized: implementing features of a highly disorganized capillary network\, representative of abnormal tissues\, in a novel hydrogel phantom\, then we should be capable of obtaining accurate and reproducible tracer kinetics through the tumor space\, allowing for the testing of image-derived pharmacokinetics.\nThis study will optimize phantom usage in radiation oncology and introduce a new 3D-printed/bio-printed adaptable phantom design that can expand scope and assess image-based pharmacokinetics of other nanoparticles\, chemotherapeutics\, and anti-cancer drugs through an apparatus that closely represents characteristics of the tumor space\, highlighting its transdisciplinary nature. Subsequently this will allow exploration how past\, present\, and future treatments behave\, and indicate potential drug-related inefficiencies\, within the tumor microenvironment.\nSupervisor Name: Catherine Coolens\nSupervisor Name: Catherine Coolens\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-brendan-samaroo/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230224T123000
DTEND;TZID=America/Toronto:20230224T130000
DTSTAMP:20230224T162229Z
CREATED:20230208T212308Z
LAST-MODIFIED:20230224T162229Z
UID:10000193-1677241800-1677243600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Travis Douglas
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Spatially defined and decorated DNA nanoparticles to investigate macrophage polarization\nAbstract: –\nSupervisor Name: Dr. Leo Chou\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-travis-douglas/
CATEGORIES:Graduate Seminar Series
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