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X-WR-CALDESC:Events for Institute of Biomedical Engineering (BME)
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DTSTART;TZID=America/Toronto:20230228T110000
DTEND;TZID=America/Toronto:20230228T120000
DTSTAMP:20230207T175407Z
CREATED:20230207T175407Z
LAST-MODIFIED:20230207T175407Z
UID:10000190-1677582000-1677585600@bme.utoronto.ca
SUMMARY:Translating 3D Bioprinting Tools From Lab to Market: an Academic’s Perspective on Starting a Company
DESCRIPTION:Please join us for an ECHO webinar featuring Prof. Stephanie Willerth\, who will provide an overview of Axolotl Biosciences\, its technologies and the story behind its success. \nAxolotl Biosciences – an award-winning spin-off company from the University of Victoria – sells high quality reagents for 3D printing human tissue models. https://www.axolotlbiosciences.com/  \n\nGuest Speaker\nProf. Stephanie Willerth\, PhD\, PEng \nChief Executive Officer\, Axolotl Biosciences \nProfessor and Canada Research Chair in Biomedical Engineering\, University of Victoria \n\nRegister in advance for this webinar. After registering\, you will receive a confirmation email containing information about joining the webinar. \nECHO is an entrepreneurship training program\, funded and organized in a partnership between (i) the Translational Biology and Engineering Program (TBEP)\, the University of Toronto component of the Ted Rogers Centre for Heart Research\, and (ii) the Health Innovation Hub (H2i). For more information\, visit: https://tedrogersresearch.ca/echo/
URL:https://bme.utoronto.ca/event/translating-3d-bioprinting-tools-from-lab-to-market-an-academics-perspective-on-starting-a-company/
CATEGORIES:External Speaker Series
ORGANIZER;CN="Translational Biology and Engineering Program (TBEP)":MAILTO:reception.tbep@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230301T120000
DTEND;TZID=America/Toronto:20230301T123000
DTSTAMP:20230301T162229Z
CREATED:20221123T192239Z
LAST-MODIFIED:20230301T162229Z
UID:10000160-1677672000-1677673800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Paul Kang
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Design\, Modeling\, and Control of a Hybrid Concentric Tube Robot and Steerable Wrist for Epilepsy Surgery\nAbstract: Epilepsy is the disease characterized by the brain generating recurrent seizures\, inducing symptoms of drop attacks\, muscle stiffening\, and loss of awareness. Traditional surgeries for epilepsy use straight and rigid tools with large craniotomies where the open exposure leads to higher morbidity rates\, greater blood loss\, and longer recovery times. Concentric tube robots (CTR) and steerable wrist instruments are two separate technologies that have potential to reduce the exposure during surgery due to their super-elasticity\, curvilinear structure\, and thin form (outer diameters less than 3mm). Despite their advantages\, CTRs are unable to make high curvature bends\, and steerable wrists are unable to create complex configurations along its usually straight backbone. These tools have been studied independently\, but very few studies have aimed to combine them to overcome each of their limitations. This thesis aims to design\, model\, and control a surgical tool that integrates these two technologies to improve the current capabilities of minimally invasive epilepsy surgery.\nSupervisor Name: Dr. James Drake\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-paul-kang/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230301T123000
DTEND;TZID=America/Toronto:20230301T130000
DTSTAMP:20230301T162229Z
CREATED:20220929T213735Z
LAST-MODIFIED:20230301T162229Z
UID:10000133-1677673800-1677675600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Nicholas Zhao
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Automated Hand Function Assessment from Egocentric Video\nAbstract:\nRestoration of arm and hand function is reported to be the top priority for rehabilitation by individuals with spinal cord injury (SCI). Clinical hand function assessments such as the Graded Redefined Assessment of Strength Sensibility and Prehension (GRASSP) are methods to evaluate the level of hand function of an individual with SCI\, but they must be done in person by a trained clinician. This restriction to an in-person clinical setting limits the accessibility of the assessment\, as well as its relevance to daily life. To address these limitations\, egocentric video is an emerging method that remotely provides detailed information about upper extremity movements\, as well as functional context. Previous works using egocentric video in rehabilitation have focused on detecting quantity of hand use and usage of compensatory grasping postures\, using deep computer vision models. However\, there have been no studies that assess the quality of hand function from egocentric video. A successful implementation of such a model would allow for automated remote monitoring of rehabilitation progress at home without requiring constant supervision from a clinician.\nThe objective of this study is to develop a deep learning model capable of predicting clinical hand function assessment scores from egocentric video. To achieve this objective\, the following research plan will be enacted: 1. Annotate a dataset with adapted GRASSP scoring. 2. Explore multiple deep learning architectures to determine the best performing model.\nSupervisor Name: Jose Zariffa\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-nicholas-zhao/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230302T120000
DTEND;TZID=America/Toronto:20230302T123000
DTSTAMP:20230302T163727Z
CREATED:20220922T213740Z
LAST-MODIFIED:20230302T163727Z
UID:10000126-1677758400-1677760200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Dana Brinson
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: A culture platform with alveolar geometry for induced pluripotent stem cell-derived distal lung organoids\nAbstract: Induced pluripotent stem cell (iPSC)-derived distal lung organoids must be improved to better recapitulate the adult alveolar epithelium. Existing organoids do not contain all relevant cell types and the cells have fetal maturity. IPSCs are an ideal source of cells for patient-specific in vitro models\, cell therapy\, and tissue engineering. Traditionally\, organoids are grown embedded in droplets of Matrigel®. This does not provide mechanical cues similar to the native lung. The physical microenvironment plays an important role in alveolar epithelial cell (AEC) differentiation. Our lab has designed PDMS substrates with hemispheres that model the alveoli. We have previously characterized growth of A549 cells or primary mouse AECs on the substrates. Primary AECs are typically grown on flat culture dishes\, and within one week alveolar type two (AT2) cells lose their phenotype and differentiate into type one (AT1) cells. We found that the biomimetic substrate maintained a more stable balance of AT1 and AT2 cells compared to flat substrates. The next step is to study iPSC-derived lung progenitor cell differentiation first on the dimpled substrates and then in more complex alveolar geometry. 3D printing will generate a complex 3D mold. Differentiation will be compared amongst cells grown on the geometries\, flat substrates\, or in traditional Matrigel® droplets. Transcriptomics and epigenomics will be used to elucidate heterogeneity in expression of genes associated with differentiation to AT1 and AT2 cells. Characterizing cells on the biomimetic substrates will help uncover whether geometric cues play a role in aiding appropriate differentiation of AECs.\nSupervisor Name: Dr. Thomas Waddell and Dr. Golnaz Karoubi\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-dana-brinson/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230302T123000
DTEND;TZID=America/Toronto:20230302T130000
DTSTAMP:20230302T163727Z
CREATED:20230118T205243Z
LAST-MODIFIED:20230302T163727Z
UID:10000185-1677760200-1677762000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Nooshin Abdollahi
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Effects of extracellular conductivity on action potential propagation.\nAbstract: Neurons use action potentials\, or spikes\, to encode and transmit information. Understanding neural coding thus requires that we understand how spikes are generated and transmitted. In myelinated axons\, spikes are transmitted rapidly and efficiently by regenerating the spikes at each node of Ranvier\, a process known as saltatory conduction. Experimental and theoretical work have demonstrated that when an action potential propagates down an axon\, it affects the extracellular electric field. As the extracellular electric field changes\, it can affect both the active and nearby axons. In this study we aimed to investigate the effects of extracellular medium on action potential propagation as well as the biophysical mechanism involved.\nSupervisor Name: Dr. Steve Prescott\nYear of Study: 5\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-nooshin-abdollahi/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230303T120000
DTEND;TZID=America/Toronto:20230303T123000
DTSTAMP:20230303T163843Z
CREATED:20220825T165236Z
LAST-MODIFIED:20230303T163843Z
UID:10000065-1677844800-1677846600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Chelsea Leung
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Developing microbubble-mediated sonoporation strategies for safe and efficient cell transfection\nAbstract: TBD\nSupervisor Name: Dr. Gang Zheng\nYear of Study: 3\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-chelsea-leung/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230303T123000
DTEND;TZID=America/Toronto:20230303T130000
DTSTAMP:20230303T163843Z
CREATED:20220831T170759Z
LAST-MODIFIED:20230303T163843Z
UID:10000086-1677846600-1677848400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Michael Valic
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Optimisation strategy for nanoparticle-based photodynamic therapy using clinical veterinary models of thyroid cancer\nAbstract:\nPhotodynamic therapy (PDT) is a nonsurgical ablative treatment strategy that can precisely target cancerous cells while sparing surrounding healthy cells. PDT involves administration of a photosensitiser drug that accumulates in tumour tissues and is activated by laser light to generate cytotoxic radical oxygen species. Delivery of photosensitisers using nanoparticles can further enhance the selectivity of drug delivery to tumour cells and improve the overall safety of PDT treatments in patients.\nThe success of PDT depends on three key treatment parameters: nanoparticle/drug dose\, drug-light interval (DLI)\, and light dose. Optimisation of these parameters are typically accomplished through pharmacokinetic and PDT efficacy studies in tumour-bearing rodents. While rodent models are convenient\, they often fail to reproduce the anatomical\, pathological\, and clinical complexities of human disease and frequently necessitate re-optimisation of PDT treatments in trial patients.\nTo overcome this translational barrier\, we have devised a strategy to optimise PDT treatment efficacy in clinical veterinary models with naturally occurring cancers prior to human clinical trials. In canine patients with resectable papillary thyroid cancer\, nanoparticle-based PDT treatments were performed varying the treatment parameters (i.e.\, nanoparticle dose\, DLI\, light dose) previously studied in rodents and the treatment efficacy evaluated with histopathology. The outcome of this study is a more robust PDT treatment protocol that can be reliably implemented in human patients with head and neck cancers.\nSupervisor Name: Gang Zheng\nYear of Study: 3\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-michael-valic/
CATEGORIES:Graduate Seminar Series
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