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X-WR-CALDESC:Events for Institute of Biomedical Engineering (BME)
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DTSTART;TZID=America/Toronto:20230308T120000
DTEND;TZID=America/Toronto:20230308T123000
DTSTAMP:20230308T165230Z
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UID:10000198-1678276800-1678278600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Shaghayegh Chavoshian
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Investigating the Influence of Obstructive Sleep Apnea on Asthma and Proposing a Prediction Model\nAbstract:\nAsthma is an inflammatory disease of the airways that can make breathing difficult and sometimes impossible. There are a variety of factors and comorbidities in asthma that can lead to respiratory insufficiency or failure such as obstructive sleep apnea (OSA). Despite the large overlap between asthma and obstructive sleep apnea\, the underlying mechanisms of the pathophysiological link between these two disorders are in their infancy. Previously\, it has been shown that the fluid accumulation in the neck and thorax while supine can be a unifying mechanism for the overlap of asthma and OSA. However\, it is not clear how the rostral fluid shift in the thorax affects airway narrowing in asthma and how it can be managed. Our central hypothesis is that one mechanism by which OSA can predispose to small airway narrowing in asthma is by increasing negative intrathoracic pressure and aggravating fluid accumulation in the thorax during sleep.\nIn this study\, we aim to address the current gaps in asthma management through three interconnected objectives. First\, we will investigate the changes in mechanical properties of airways in patients with asthma and OSA due to increased negative intrathoracic pressure and thoracic fluid volume (TFV). Second\, we will investigate if OSA treatments by either removing intrathoracic pressure or reducing TFV would alleviate overnight narrowing in airways in populations with asthma and OSA. Third\, we will develop a model to predict asthma worsening by monitoring electrocardiogram (ECG) and respiration signals.\nBy accomplishing the objectives of this study\, more information about the interaction between asthma and OSA will be gained. Furthermore\, with the help of monitoring ECG and respiration signals\, there will be better ways for frequent monitoring of airway narrowing in asthma\, which may help develop better tools to manage asthma\, especially in those with asthma and OSA.\nSupervisor Name: Dr. Azadeh Yadollahi\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-shaghayegh-chavoshian/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230308T123000
DTEND;TZID=America/Toronto:20230308T130000
DTSTAMP:20230308T165231Z
CREATED:20230113T203750Z
LAST-MODIFIED:20230308T165231Z
UID:10000183-1678278600-1678280400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Anat Usatinsky
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Implantable\, battery-free\, Bluetooth-enabled\, multiwavelength spectroscopy device for the remote monitoring of physiological biomarkers\nAbstract: Spectroscopy use is limited due to the innate limitation of light penetration depth. The recent miniaturization of optical sensors and advanced microprocessors enabled the use of spectroscopy systems in compact implantable formats. Our lab aims to evaluate the use of spectral sensors to monitor physiological biomarkers via a clinically translational implant. We integrated the miniaturized spectrometers onto implantable platforms allowing for red and near-infrared LED capabilities. We then demonstrated its functionality via in-vitro studies and in-vivo rodent studies. The data received was analyzed for breathing rate and heart rate. By showing that our technology could detect these biomarkers\, we demonstrate the use of the first-of-its-kind\, implantable\, multi- wavelength\, Bluetooth-operated\, RF utilizing\, modular-biosensor\, in tracking deep tissue hemodynamics. Currently\, we are further displaying device vitality in clinical settings via hypoxia studies and extending its wireless power capabilities.\nSupervisor Name: Dr. Daniel Franklin\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-anat-usatinsky/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230309T120000
DTEND;TZID=America/Toronto:20230309T123000
DTSTAMP:20230309T165237Z
CREATED:20230110T202256Z
LAST-MODIFIED:20230309T165237Z
UID:10000177-1678363200-1678365000@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Emilio Garcia Flores
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: The role of neural precursor cells in metformin-mediated recovery following spinal cord injury.\nAbstract: Spinal cord injury (SCI) is a common cause of death\, paralysis\, and other debilitating conditions. Although SCI begins as a traumatic event\, damage to the spinal cord (SC) continues in the following weeks in the form of neuronal cell death and demyelination\, the loss of oligodendrocytes. Currently\, there are limited therapeutic interventions aimed at promoting cellular repair\, however we have previously found that treatment with metformin\, a common Type II diabetes drug\, results in improved functional outcomes in mice. Correlated with these results\, we also observed 1) enhanced proliferation of endogenous neural precursor populations like the Sox2+ neural stem & progenitor cells (NSPCs) and the NG2+ oligodendrocyte progenitor cells (OPCs)\, as well as 2) increased oligodendrogenesis following metformin treatment. Here\, we explore whether NSPCs or OPCs (and both their roles in oligodendrogenesis) are required for metformin-mediated recovery. We hypothesize that NSPCs are required for metformin-mediated recovery\, and OPC are not. Using a Sox2TK ablation model\, we first propose to explore whether proliferating NSPCs are required for metformin-mediated recovery. Next\, using Sox2- and NG2- specific knockout models of Myrf (a transcription factor essential for oligodendrogenesis)\, we propose to test whether OPC- or NSPC-derived oligodendrogenesis is required for metformin-mediated recovery. Presently we have generated these models and validated them using both and in vitro and in vivo approaches. Notably\, preliminary results from our Sox2TK ablation model indicate that in the absence of proliferating NPSCs metformin-mediated recovery is lost. Together with ongoing Myrf knockout studies\, these findings will begin to elucidate the cellular basis for metformin-mediated recovery and help establish it as a therapeutic intervention aimed at promoting cellular repair.\nSupervisor Name: Dr. Cindi Morshead\nYear of Study: 2\nProgram of Study: MASc\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-emilio-garcia-flores/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230309T123000
DTEND;TZID=America/Toronto:20230309T130000
DTSTAMP:20230309T165237Z
CREATED:20230118T205244Z
LAST-MODIFIED:20230309T165237Z
UID:10000186-1678365000-1678366800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Siti Nurfaezah Binti Zahari
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: MACHINE LEARNING-DRIVEN SENSORY ASSESSMENT OF SPINAL CORD INJURY\nAbstract: Spinal cord injury (SCI) often results in sensory deficits\, which can significantly impact the quality of life of affected individuals. Traditional methods of sensory assessment\, such as ISNCSCI using pinprick and light touch\, have limitations. Recently\, researchers have developed the Electrical Perceptual Threshold (EPT) test for sensory assessment\, which is considered a better method than traditional ones. However\, the current EPT test is performed manually\, which increases the risk of human error and bias. In this research study\, we propose to develop a computer-controlled EPT test using a controlled relay circuit for the sensory assessment of patients with SCI. The electrodes will be placed at 56 dermatomes before the stimuli begin. The computer-controlled EPT test will automatically control the stimulus intensity and deliver it through the electrodes at the ASIA points in random order. The aim of this study is to investigate the reliability and validity of the computer-controlled EPT test using a controlled relay circuit in comparison to traditional methods of sensory assessment in patients with SCI. In addition\, we also aim to use machine learning approaches to predict the extent of recovery in patients with sensory deficits at 12 or 24 months post-injury and identify potential predictors of recovery outcomes. We will collect data from 20 healthy subjects and 80 subjects with SCI. For healthy subjects\, the subjects will be in the same age group as males and females. While for subjects with SCI\, different ages for males and females will be collected. The data from SCI subjects will take from multiple time points\, such as one month\, three months\, six months and twelve months\, to track their recovery over time. We expect that the computer-controlled EPT test using a controlled relay circuit will be more accurate\, reliable\, and efficient than traditional methods of sensory assessment in patients with SCI and that it will help to improve the prediction of recovery outcomes.\nSupervisor Name: Prof Milos R Popovic and Dr Shehroz Khan\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-siti-nurfaezah-binti-zahari/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230310T120000
DTEND;TZID=America/Toronto:20230310T123000
DTSTAMP:20230310T165253Z
CREATED:20221005T215237Z
LAST-MODIFIED:20230310T165253Z
UID:10000144-1678449600-1678451400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Zahra Sepahi
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Warren Chan\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-zahra-sepahi/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230310T123000
DTEND;TZID=America/Toronto:20230310T130000
DTSTAMP:20230310T165253Z
CREATED:20230207T212236Z
LAST-MODIFIED:20230310T165253Z
UID:10000191-1678451400-1678453200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Ryan Lee Chan
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Functionalized DNA for Templated Biomineralization\nAbstract: DNA assemblies show promising biomimicry; they can fold into complex and highly ordered nanoarchitectures capable of mimicking naturally occurring structures. Further\, they can act as scaffolds and be functionalized at specific locations. To date\, there is limited research on DNA assemblies as guides for mineral growth. The objective is to develop DNA nanostructures functionalized with a mineral promoting peptide at precise locations to control mineralization. It is hypothesized that enhanced and selective mineral growth will occur by controlling nucleation sites using peptide-DNA nanostructures.\nSupervisor Name: Dr. Karina Carneiro\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-ryan-lee-chan-2/
CATEGORIES:Graduate Seminar Series
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