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X-WR-CALDESC:Events for Institute of Biomedical Engineering (BME)
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DTSTART;TZID=America/Toronto:20230329T120000
DTEND;TZID=America/Toronto:20230329T123000
DTSTAMP:20230328T172229Z
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SUMMARY:Graduate Seminar Series: Clinical Stream - Yupeng Tian
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: A Firing Rate Network Model on the Thalamic Deep Brain Stimulation\nAbstract:\nDeep brain stimulation (DBS) is a standardized therapy of many neurological motion disorders\, e.g.\, Parkinson’s disease and essential tremor. However\, the DBS therapeutic mechanisms on the disease-related neuronal networks remain elusive. DBS mechanism detection is challenging due to insufficient quantitative understandings and the sparsity of human data. For human subjects\, neuronal data can only be recorded with safe parameter settings on a very small proportion of neurons.\nWe developed a firing rate network model on the neuronal circuits receiving DBS\, and implemented the model in investigating the network mechanism underlying the thalamus-DBS in treating essential tremor. We accurately reproduced the experimental single-unit recordings on the neurons in thalamic ventral intermediate nucleus (Vim) during DBS; the model fit is precise and consistent across various DBS frequencies (5~200Hz). We found the role of inhibitory nuclei is critical in stabilizing the network and accurately fitting the experimental data. Our model can be potentially implemented in optimizing the DBS frequencies for maximal clinical effects.\nSupervisor Name: Milos Popovic and Milad Lankarany\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-yupeng-tian/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230329T123000
DTEND;TZID=America/Toronto:20230329T130000
DTSTAMP:20230328T172229Z
CREATED:20221124T192233Z
LAST-MODIFIED:20230328T172229Z
UID:10000161-1680093000-1680094800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Clinical Stream - Lindsay Stern
DESCRIPTION:Graduate Seminar Series: Clinical Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: A Novel Approach for Body Position Monitoring during Sleep using a Smart Mat\nAbstract: TBD\nSupervisor Name: Atena Roshan-Fekr\, Geoff Fernie\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-clinical-stream-lindsay-stern/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230330T120000
DTEND;TZID=America/Toronto:20230330T123000
DTSTAMP:20230329T172322Z
CREATED:20220825T165236Z
LAST-MODIFIED:20230329T172322Z
UID:10000068-1680177600-1680179400@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Safwat Khan
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Defining and validating a pancreatic tissue-specific endothelial cell transcriptional signature\nAbstract: The vasculature shows intricate tissue-specific structural and functional heterogeneity. Vessels in the pancreas display specialized structures\, called fenestrae\, which allow for rapid glucose sensing and response by insulin secreting β-cells. Moreover\, intra-islet ECs have been implicated in a unique cross-talk with β-cells\, which is essential for their survival and function. We reasoned that a unique\, pancreas-specific molecular signature enables ECs to adopt a pancreatic-specific microvascular identity\, specializing them to support glucose/Islet function and homeostasis. To uncover this signature\, we have performed a meta-analysis of published single-cell and single-nuclei RNA-sequencing datasets of the pancreas. Using multi-organ gene expression atlases we have uncovered and validated a pancreas-specific endothelial gene signature. We also introduce a transcriptomic map of human pancreatic ECs integrating 3 human pancreas EC datasets. We define gene signatures for different vascular bed segments within the pancreas\, including 2 unique capillary populations\, which are reminiscent of exocrine pancreas ECs and islet-like/endocrine ECs. We have validated our transcriptomic profile using RNAScope and immunofluorescence staining on mouse e18.5 pancreatic tissue cross-sections. Further characterization of our pancreas-specific endothelial gene signatures and vascular subtype signatures within the pancreas will provide novel insights into the molecular mechanisms that drive islet EC specialization in glucose homeostasis and their role in diabetes.\nSupervisor Name: Sara Vasconcelos\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-safwat-khan/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230330T123000
DTEND;TZID=America/Toronto:20230330T130000
DTSTAMP:20230329T172322Z
CREATED:20221011T220810Z
LAST-MODIFIED:20230329T172322Z
UID:10000147-1680179400-1680181200@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Cell and Tissue Stream - Omar Mourad
DESCRIPTION:Graduate Seminar Series: Cell and Tissue Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Modeling HFpEF-like diastolic dysfunction in a heart-on -a-chip platform\nAbstract: TBD\nSupervisor Name: Sara Vasconcelos\nYear of Study: 4\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-cell-and-tissue-stream-omar-mourad/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230331T120000
DTEND;TZID=America/Toronto:20230331T123000
DTSTAMP:20230330T173744Z
CREATED:20220901T170736Z
LAST-MODIFIED:20230330T173744Z
UID:10000088-1680264000-1680265800@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - Colin Blackadar
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: Tbd\nAbstract: Tbd\nSupervisor Name: Warren Chan\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-colin-blackadar/
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230331T123000
DTEND;TZID=America/Toronto:20230331T130000
DTSTAMP:20230330T173744Z
CREATED:20220901T170736Z
LAST-MODIFIED:20230330T173744Z
UID:10000089-1680265800-1680267600@bme.utoronto.ca
SUMMARY:Graduate Seminar Series: Molecular Stream - bram bussin
DESCRIPTION:Graduate Seminar Series: Molecular Stream\nGraduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for molecular stream presenters.\nIf you would like to invite your Principal Investigator\, please add their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nPresentation Title: TBD\nAbstract: TBD\nSupervisor Name: Warren Chan\nYear of Study: 2\nProgram of Study: PhD\nZoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09\nMeeting ID: 896 1037 2821\nPassword: 483329\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-seminar-series-molecular-stream-bram-bussin/
CATEGORIES:Graduate Seminar Series
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