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SUMMARY:BRI Research Rounds research talk with Dr. Tom Chau
DESCRIPTION:Featured Speaker: Tuesday\, May 2nd\, 2023\, noon to 1 p.m. EST \nWe’re pleased to invite you to hear from our next guest speaker\, Dr. Tom Chau\, a senior scientist\, and a full professor of biomedical engineering at the University of Toronto. He also leads the PRISM Lab (Paediatric Rehabilitation Intelligent Systems Multidisciplinary) \nDr. Chau will present his research talk titled\, Brain-computer interfaces as access technologies for children and youth with disabilities: It’s the thought that counts. \nResearch Talk Summary: \nDr. Chau’s talk will focus on some recent advances in non-invasive brain-computer interfaces (BCIs) developed at Holland Bloorview as an alternative access pathway to communication and environmental control. BCIs directly harness brain activity associated with functional intent and thereby bypass the motor system in connecting people to the world around them. At Holland Bloorview\, we have been investigating near-infrared spectroscopic BCIs\, neuroelectric BCIs\, ultrasonic BCIs and some combinations thereof. Each modality will be briefly introduced\, and a sampling of novel BCI control paradigms will be exemplified. We are only beginning to understand the enabling and therapeutic potential of BCIs in the development of children. The presentation will close with a description of how these technologies are being translated into clinical practice at Holland Bloorview. \nTo register for the event\, visit: hollandbloorview.ca/BRIResearchRounds. \nInterested in learning more about our future speakers? Please email BRIresearchrounds@hollandbloorview.ca to be added to our mailing list.
URL:https://bme.utoronto.ca/event/bri-research-rounds-research-talk-with-dr-tom-chau/
CATEGORIES:External Speaker Series
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/04/Tom-Chau.jpg
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DTSTAMP:20230421T131146Z
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SUMMARY:BME Faculty Search Seminar - Kibaek Choe
DESCRIPTION:In Vivo Live Cell Imaging by Three-Photon (3P) Microscopy\nDr. Kibaek Choe\,\nPostdoctoral Associate\, Cornell University\nIn vivo confocal and two-photon (2P) microscopies have been a major driving force in deepening our understanding of cell dynamics by enabling the visualization of migration\, distribution\, morphology\, and cell-cell interactions in three dimensions and at subcellular resolution. In this talk\, I will first discuss the key features of confocal and 2P microscopes for in vivo imaging and introduce bio-applications in various mouse organs such as the small intestine\, bone marrow\, and lymph nodes. \nSecondly\, I will talk about 3P microscopy\, which overcomes the depth limitation of confocal and 2P imaging. We applied 3P microscopy to visualize dynamic immune cell behavior in mouse lymph nodes for the first time. We determined safe laser parameters by monitoring immune cell motility in various imaging conditions to prevent photo-damage. Using the safe laser conditions\, we were able to visualize blood vessels through the entire depth of mouse popliteal lymph node in vivo. Additionally\, we could measure the motility of CD4+ and CD8+ T cells through the entire depth of T cell zone in vivo\, allowing us to discover the depth dependence of CD4+ T cell motility in the T cell zone during lipopolysaccharide-induced inflammation. \nThus\, in vivo 3P microscopy has the potential to uncover previously unknown cellular dynamics in deeper regions of many other organs beyond the depth limit of conventional confocal and 2P microscopies. \nTalk will be in-person and virtual\, see information below.
URL:https://bme.utoronto.ca/event/bme-faculty-search-seminar-kibaek-choe/
LOCATION:MS3153
CATEGORIES:BME Faculty Search
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