BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Institute of Biomedical Engineering (BME) - ECPv6.17.4.1//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Institute of Biomedical Engineering (BME)
X-ORIGINAL-URL:https://bme.utoronto.ca
X-WR-CALDESC:Events for Institute of Biomedical Engineering (BME)
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/Toronto
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20220313T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20221106T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20230312T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20231105T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20240310T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20241103T060000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230518T090000
DTEND;TZID=America/Toronto:20230518T100000
DTSTAMP:20230516T203337Z
CREATED:20230515T152033Z
LAST-MODIFIED:20230516T203337Z
UID:10000223-1684400400-1684404000@bme.utoronto.ca
SUMMARY:BME Faculty Search Seminar - Ilke Uguz
DESCRIPTION:Development of High-Density Active Neural Interfaces using Conjugated Polymers\nDr. Ilke Uguz\nPostdoctoral Research Associate\, Columbia University\nPrecise\, stable\, and biocompatible neural interfaces are crucial for effective brain-machine interfaces and therapeutic interventions. Conjugated polymers offer exceptional potential for such applications\, owing to their softness\, biocompatibility\, and mixed ionic and electronic charge transport properties. By integrating CPs at the front-end\, we can achieve active pixels comparable in size to individual neurons while maintaining mechanical properties similar to surrounding tissue. During the talk\, I will delve into microfabrication and design strategies used to develop implantable CP-based neural interfaces with electrical and optical functionalities. Specifically\, I will address the technological challenges associated with scalability and present examples that demonstrate the successful generation of complex circuitries on flexible substrates\, as well as their monolithic integration onto drive electronics. Additionally\, I will demonstrate large-scale electrophysiology and optogenetic manipulation of neuronal circuits with high spatiotemporal resolution\, highlighting the potential of CPs as a foundation for high-density active front-end arrays. \nTalk will be virtual only\, see information below.
URL:https://bme.utoronto.ca/event/bme-faculty-search-seminar-ilke-uguz/
CATEGORIES:BME Faculty Search
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/05/Ilke-Uguz.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230518T180000
DTEND;TZID=America/Toronto:20230518T190000
DTSTAMP:20230425T141531Z
CREATED:20230425T141510Z
LAST-MODIFIED:20230425T141531Z
UID:10000218-1684432800-1684436400@bme.utoronto.ca
SUMMARY:Operability of the heart lung machine
DESCRIPTION:
URL:https://bme.utoronto.ca/event/operability-of-the-heart-lung-machine/
CATEGORIES:External Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230519T130000
DTEND;TZID=America/Toronto:20230519T140000
DTSTAMP:20230509T183039Z
CREATED:20230509T183039Z
LAST-MODIFIED:20230509T183039Z
UID:10000221-1684501200-1684504800@bme.utoronto.ca
SUMMARY:BME Faculty Search Seminar - Nova Pishesha
DESCRIPTION:Exploiting Antigen Presentation Pathways for Precision Immune Engineering \nDr. Nova Pishesha\,\nJunior Fellow\, Society of Fellows at Harvard University\nCurrent treatments for autoimmunity rely on general immunosuppression\, which exposes patients to opportunistic infections. Hence\, immunoregulatory modalities\, which educate the immune system to induce antigen-specific tolerance are desirable. My doctoral research revolved around engineered red blood cells (RBCs) to treat preclinical models of autoimmune diseases by hijacking the tolerogenic RBC clearance pathways. As a postdoctoral fellow\, I worked on an alpaca-derived single domain antibody fragment (nanobody)-based platform. I have engineered these nanobodies to efficiently target antigen presenting cells and transmit either tolerogenic or vaccinal signal to antigen-specific immune cells. I showed that a single dose of a VHH that recognizes major histocompatibility complex class II/MHCII (VHHMHCII)\, conjugated to a myelin peptide and an anti-inflammatory corticosteroid\, i.e. dexamethasone (VHHMHCII-MOG-DEX)\, affords lasting protection in a mouse model of multiple sclerosis (MS). A single dose of VHHMHCII-MOG-DEX also reverses paralyses in mice without compromising the capacity of the immune system to fight pathogens. I further developed this technology for treating type 1 diabetes and as a SARS-CoV-2 vaccine. My independent group will aspire to produce novel treatments for autoimmune and infectious diseases. \nTalk will be in-person and virtual\, see information below.
URL:https://bme.utoronto.ca/event/bme-faculty-search-seminar-nova-pishesha/
LOCATION:MS3153
CATEGORIES:BME Faculty Search
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2023/05/1517545306211.jpg
END:VEVENT
END:VCALENDAR