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DTSTART;TZID=America/Toronto:20250106T171000
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UID:10000514-1736183400-1736184300@bme.utoronto.ca
SUMMARY:Graduate Student Seminar Series - Bojing Gui
DESCRIPTION:Graduate Student Seminar Series\nPlease ensure you invite your Principal Investigator by adding their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nLocation: HS610 – 155 College St\, Room 610\nPresentation Title: Investigating Cortical Involvement and Spinal Excitability in the Control of Standing Posture\nAbstract:\nPostural control involves integration of sensory inputs and motor commands within the spinal cord and brain. While studies have investigated the role of descending corticospinal commands and spinal reflexes in maintaining balance using methods such as motor evoked potentials (MEPs) using transcranial magnetic stimulation (TMS) and H-reflexes using peripheral nerve stimulation\, the exact pathways involved remain unclear. We aim to contribute to this understanding by exploring the effects of posture on spinal motoneurons by utilizing F-waves as a direct measure of their excitability. Furthermore\, we wish to further investigate corticospinal and spinal pathways by isolating the effects of body position and both voluntary and postural muscle activity to understand the specific factors influencing postural control.\nData collection from healthy participants is ongoing. Participants performed four tasks: natural standing\, supported standing with voluntary muscle contraction\, supported standing\, and sitting. Electromyographic signals from the soleus\, medial head of gastrocnemius\, and tibialis anterior muscles was recorded. Visual feedback was used to ensure consistent muscle activity during voluntary contraction to match natural standing. Soleus F-waves\, H-reflexes\, and MEPs were measured.\nResults from 16 participants (8F) indicate that MEP measures of cortical excitability show modulation of the silent period. A shorter silent period in voluntary activation indicates decreased cortical inhibition\, thus increased cortical excitability compared to standing. Meanwhile\, F-wave measurements of spinal excitability shows that spinal motoneuron excitability is not modulated by position or activity. This indicates that modulation due to voluntary activation does not originate in the spinal cord. Thus\, voluntary activation involves increased cortical control\, while postural control has greater involvement of subcortical structures despite matched position\, muscle activity\, and spinal excitability.\nSupervisor Name: Kei Masani\nYear of Study: 3\nProgram of Study: MASc\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-student-seminar-series-bojing-gui/
LOCATION:HS610
CATEGORIES:Graduate Seminar Series
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DTSTART;TZID=America/Toronto:20250107T120000
DTEND;TZID=America/Toronto:20250107T130000
DTSTAMP:20250107T142729Z
CREATED:20240806T134944Z
LAST-MODIFIED:20250107T142729Z
UID:10000426-1736251200-1736254800@bme.utoronto.ca
SUMMARY:Invited Academic Seminar Series - Jaideep Bains
DESCRIPTION:Speaker\nJaideep Bains\nDirector \nKrembil Research Institute\nUniversity Health Network \n\n\nPlease join us as Jaideep Bains\, Director of the Krembil research Institute\, shares his research with us.\nResearch Summary\nDr. Bains’ research uses multiple experimental approaches to reveal key features about neural circuits that regulate internal state and are also purposed to control behavior and store information in response to challenges. Specifically\, his lab uses in vitro slice electrophysiology\, in vivo imaging\, optogenetics\, behavioral analysis tools and physiological assays to characterize neural circuits that decode stress\, modify internal states and generate specific coping behaviors. One of his goals is to better understand the mechanisms that allow these circuits\, or specific cell populations\, to store information related to the modality\, intensity and temporal features of stress. In addition to his extensive experience in synaptic physiology and electrophysiology he has used circuit mapping approaches to link activity in specific cell populations to different behaviors. His work has linked brief stress exposure and enduring synaptic changes in the hypothalamus (reviewed in Bains et al\, Nat Rev Nsci\, 2015). His lab has provided clear evidence supporting a role for astrocytes in controlling the strength of excitatory synapses in the hypothalamus (Gordon et al\, Nat Nsci\, 2005\, Neuron\, 2009). More recently\, his lab has shown new roles for hypothalamic CRH neurons as bottom-up controllers for complex behaviors associated with stress coping (Fuzesi et al\, Nat Comm\, 2016)\, the transmission and detection of affective states between mice (Sterley et al\, Nat Nsci\, 2018) and linking stress controllability and active behaviour strategies (Daviu et al\, Nat Nsci\, 2020).
URL:https://bme.utoronto.ca/event/invited-academic-seminar-series-jaideep-bains/
LOCATION:MP202\, 255 Huron Street\, Toronto\, Ontario\, M5S1A7\, Canada
CATEGORIES:BME Invited Academic Speaker Series
ATTACH;FMTTYPE=image/jpeg:https://bme.utoronto.ca/wp-content/uploads/2024/08/Jaideep-Bains-Talk-2025.jpeg
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DTSTART;TZID=America/Toronto:20250109T160000
DTEND;TZID=America/Toronto:20250109T170000
DTSTAMP:20250109T145438Z
CREATED:20250109T145438Z
LAST-MODIFIED:20250109T145438Z
UID:10000536-1736438400-1736442000@bme.utoronto.ca
SUMMARY:PM Seminar Series - Dr. Eun Ji Chung of USC\, January 9\, 2025
DESCRIPTION:Title:        “Designing nanomedicine for genetic and chronic diseases” \n\nSpeaker:          Eun Ji Chung\, PhD \nDr. Karl Jacob Jr and Karl Jacob III Early Career Chair \nAssociate Professor of Biomedical Engineering\, Chemical Engineering and Materials Science\, Surgery\, and Medicine \nUniversity of Southern California \n\n  \n\nDate:               Thursday\, January 9\, 2025 \nTime:               4:00 – 5:00 pm \n  \nLocation:         Princess Margaret Cancer Centre\, 610 University Ave\, 6th floor\, Bob Bell Auditorium \n  \nHost:                Dr. Gang Zheng
URL:https://bme.utoronto.ca/event/pm-seminar-series-dr-eun-ji-chung-of-usc-january-9-2025/
CATEGORIES:External Speaker Series
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