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X-WR-CALDESC:Events for Institute of Biomedical Engineering (BME)
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DTSTART;TZID=America/Toronto:20261023T161000
DTEND;TZID=America/Toronto:20261023T161500
DTSTAMP:20260912T170810Z
CREATED:20260909T143109Z
LAST-MODIFIED:20260912T170810Z
UID:10000754-1792771800-1792772100@bme.utoronto.ca
SUMMARY:Graduate Student Seminar Series - Hugo Higueros
DESCRIPTION:Graduate Student Seminar Series\nPlease ensure you invite your Principal Investigator by adding their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nLocation: MS2158 – 1 King’s College Circle\nPresentation Title: Implantable Devices with Multimodal Sensing Capabilities for the Assessment of Deep Tissue\nAbstract: Conventional non-invasive optical and bioelectrical approaches for the assessment of hemodynamic and fibrotic states remain limited in their ability to interrogate deep tissue. This work presents a series of unimodal and multimodal implants featuring multi-wavelength photoplethysmography (PPG) and bioimpedance (BIOZ) sensing capabilities. The implants are evaluated in healthy and fibrotic disease models and under a variety of hemodynamic challenges\, enabling blood-volume-invariant tissue oximetry and the identification of novel fibrotic biomarkers.\nSupervisor Name: Dr. Daniel Franklin\nYear of Study: 5\nProgram of Study: PhD\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-student-seminar-series-hugo-higueros-2/
LOCATION:MS2158
CATEGORIES:Graduate Seminar Series
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BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20261023T161500
DTEND;TZID=America/Toronto:20261023T162000
DTSTAMP:20260912T170810Z
CREATED:20260909T143109Z
LAST-MODIFIED:20260912T170810Z
UID:10000755-1792772100-1792772400@bme.utoronto.ca
SUMMARY:Graduate Student Seminar Series - Zoe Paraskevopoulos
DESCRIPTION:Graduate Student Seminar Series\nPlease ensure you invite your Principal Investigator by adding their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nLocation: MS2158 – 1 King’s College Circle\nPresentation Title: Optimizing Deep Brain Stimulation for Essential Tremor\nSupervisor Name: Milad Lankarany\nYear of Study: 2\nProgram of Study: PhD\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-student-seminar-series-zoe-paraskevopoulos/
LOCATION:MS2158
CATEGORIES:Graduate Seminar Series
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BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20261023T162000
DTEND;TZID=America/Toronto:20261023T162500
DTSTAMP:20260912T170810Z
CREATED:20260909T143109Z
LAST-MODIFIED:20260912T170810Z
UID:10000757-1792772400-1792772700@bme.utoronto.ca
SUMMARY:Graduate Student Seminar Series - Luka Zigomanis
DESCRIPTION:Graduate Student Seminar Series\nPlease ensure you invite your Principal Investigator by adding their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nLocation: MS2158 – 1 King’s College Circle\nPresentation Title: Alternative Approaches to Quantifying Brain-Muscle Connectivity\nSupervisor Name: Kei Masani\nYear of Study: 3\nProgram of Study: PhD\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-student-seminar-series-luka-zigomanis/
LOCATION:MS2158
CATEGORIES:Graduate Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20261023T162500
DTEND;TZID=America/Toronto:20261023T163000
DTSTAMP:20260912T170810Z
CREATED:20260909T143109Z
LAST-MODIFIED:20260912T170810Z
UID:10000756-1792772700-1792773000@bme.utoronto.ca
SUMMARY:Graduate Student Seminar Series - Fanglin Gong
DESCRIPTION:Graduate Student Seminar Series\nPlease ensure you invite your Principal Investigator by adding their email via the ‘Add Guest’ button and they will also be notified of your presentation.\nLocation: MS2158 – 1 King’s College Circle\nPresentation Title: Lipid nanoparticles optimized for large RNA cargo enhance genome editing in mouse liver\, lung and brain\nAbstract: Non-viral delivery of large gene editors remains a major barrier to unlocking the therapeutic potential of genome editing. Although lipid nanoparticles (LNPs) are clinically validated for RNA delivery\, their efficacy often declines when encapsulating larger mRNA transcripts necessary for genome editing. In this work\, we present a large-cargo-informed lipid discovery strategy that incorporates mRNA size into the rational design and screening of LNPs. By synthesizing a library of over 300 unique ionizable lipid candidates and evaluating their performance using multi-kilobase reporter mRNAs\, we identified a class of large-cargo-optimized lipids (LC-lipids). The lead ionizable lipid\, LC-1\, enabled improved Cas9 gene knockout and adenine base editing across multiple tissue types and administration routes\, including the liver (intravenous)\, brain (intrathecal)\, and lung (intratracheal)\, consistently outperforming benchmark LNPs using LP-01 and ALC-0315 as the ionizable lipid.\nSupervisor Name: Dr. Bowen Li\nYear of Study: 4\nProgram of Study: PhD\nPowered by Calendly.com
URL:https://bme.utoronto.ca/event/graduate-student-seminar-series-fanglin-gong-3/
LOCATION:MS2158
CATEGORIES:Graduate Seminar Series
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