Graduate Seminar Series: Clinical Stream – Megh Rathod

Graduate Seminar Series: Clinical Stream
Graduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for clinical stream presenters.
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Presentation Title: Development of Accurate and Equitable Wearable Non-Invasive Optical Devices for Continuous Hemodynamic Monitoring
Abstract:
The prevalence of heart failure (HF) is increasing with an estimated 26 million people affected worldwide. Current patient monitoring tools are often inconvenient, uncomfortable, and limited in application and accuracy. This has led to the rise of non-invasive continuous monitoring devices, known as wearables. Advances in wearable technologies are led by miniaturized sensors, predominantly optoelectronic – which leverage light-tissue interactions to monitor physiology.
However, existing non-invasive tools rely on numerous assumptions about the physiology of the user, and often do not account for forms of interpersonal variability (e.g. the presence of melanin in the skin). This work aims to develop optoelectronic strategies for continuous remote monitoring of metrics using multiwavelength (MW) photoplethysmography. To achieve this, I will implement miniaturized MW spectroscopy platforms into wearable electronic devices and develop algorithms that estimate these physiological metrics and account for interpersonal variability. The custom-developed wearable will use MW photoplethysmography via miniature spectrometers and light sources (across 400 nm – 1000 nm) and will be tested via simulations, phantoms, and bench tests before clinical validation.
This work will demonstrate a methodology for skin-tone invariant cardiovascular metrics relevant to both clinical-grade and commercial health monitors. Optical sensors will serve a major role in the future of physiological monitoring, however, correcting this technology is a key refinement needed to prevent the perpetuation of inaccuracies in marginalized groups. Implementation into a wearable device will allow continuous monitoring of cardiac health that may improve patient outcomes and predict catastrophic events.
Supervisor Name: Dr. Daniel Franklin (BME) and Dr. Heather Ross (Medicine)
Year of Study: 2
Program of Study: PhD
Zoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09
Meeting ID: 896 1037 2821
Password: 483329
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