Posts Categorized: News

New co-delivery method for efficient siRNA and small molecule drug transport

Researchers at the University of Toronto have developed a method for co-delivering therapeutic RNA and potent drugs directly into cells, potentially leading to a more effective treatment of diseases in the future. This research, recently published in Advanced Materials, explores how ionizable drugs can be used to co-formulate small interfering RNA (siRNA) for more effective intracellular delivery.

Physiatry, 3D Printed Prosthetics, and the Intersection of Engineering & Medicine: A Chat with Alumnus Dr. Amanda Mayo

After completing her MHSc at BME in 2004, Dr. Amanda Mayo transitioned into medicine, specializing in Physiatry, also known as Physical Medicine and Rehabilitation. Recently promoted to Chief of the St. John’s Rehab Program at Sunnybrook Health Sciences Centre, Dr. Mayo has dedicated over a decade to advancing patient care, collaborating on accessible prosthetics, and leading and mentoring in her field.

Empowering and educating entrepreneurship in cardiovascular translation

The Entrepreneurship for Cardiovascular Health Opportunities (ECHO) Program was founded by Dr. Soror Sharifpoor in 2018. Aimed at improving cardiovascular research commercialization, this 12-month program includes workshops, webinars, networking, and mentorship activities, culminating in a public pitch competition where ventures can win $250,000 in startup funding.

Five BME faculty members & collaborators receive a combined $2.6mil+ funding from CIHR

Professors Hai-Ling Margaret Cheng, Leo Chou, Daniel Franklin, Naomi Matsuura, and Cari Whyne and their collaborators have received a combined funding of $2.6mil+ from the Canadian Institute of Health Research (CIHR) as a part of the 2024 Spring CIHR Project Grant. The CIHR Project Grant program funds innovative health research projects with the potential to significantly advance health knowledge, healthcare, health systems, and health outcomes.

New technique improves measurement of cell barriers

Researchers at the University of Toronto have developed a novel, cost-effective method called Porous Membrane Electrical Cell–Substrate Impedance Spectroscopy (PM-ECIS) to assess the function of biological barriers in Petri dishes. In a subsequent study, the researchers characterized its sensitivity and further validated the method against a gold-standard barrier assessment technique. This new method could enhance research in fields like drug development and disease modeling.
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