Graduate Seminar Series: Cell and Tissue Stream
Graduate Seminar Series for the Institute of Biomedical Engineering (BME). This day is for cell and tissue stream presenters.
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Presentation Title: Craniomaxillofacial restoration: Innovative tool development to aid nasal reconstruction
Abstract: The craniomaxillofacial (CMF) anatomy is a complex 3D structure composed of soft tissues covering an intricately shaped skeletal foundation. Traumatic injury can negatively impact CMF form and function (psychosocial and physical well-being). In post-traumatic reconstructive nasal reconstruction, septal cartilage (which provides the foundation of structure and support to the nasal airway) is often deficient and struts from costal (rib) cartilage are used to re-create the central “L strut” support through a labor-intensive manual approach. The major disadvantage of using costal cartilage is its tendency to warp and various clinical techniques have been suggested to try to carve straight struts from costal cartilage (overcoming warping) to recreate the “L strut”. Specifically, cartilage harvested autologously from the synchondrosis junction between the 6th and 7th rib of the patient cut into slices a few millimeters thick has been used to recreate the struts of the nasal septum. In this, transverse slicing has shown significantly less graft warp and the ability to yield multiple struts from one piece of harvested rib. It has been postulated that the lower tendency for graft warp using this technique may be due to the directionality of slicing, preserving the balance of cross-sectional forces. Manual preparation of grafts may result in an imbalance of these forces resulting in the unwanted warp (due to cartilage anisotropy) and the consequent paucity of useable graft material.
Supervisor Name: Drs. Cari Whyne and Jeff Fialkov
Year of Study: 2
Program of Study: MASc
Zoom link: https://us02web.zoom.us/j/89610372821?pwd=azd4SCtYVWtreVovaGNPV1c2NGY2Zz09
Meeting ID: 896 1037 2821
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