Posts Tagged: Cell & Tissue Engineering
The Discovery Grant program is dedicated to supporting researchers as they venture into new territories to find solutions to pressing issues such as environmental protection, food security, and sustainable construction in cold climates. It aims to promote and maintain a diverse and high-quality research capability in the natural sciences and engineering at Canadian universities, foster research excellence, and provide a stimulating environment for research training.
Researchers at the University of Toronto have developed a new miniaturized assay platform, mini-MEndR, designed to evaluate muscle stem cell-mediated repair in a more efficient and scalable manner. This novel platform, funded by CFREF “Medicine by Design”, represents a significant advancement in the field of regenerative medicine, offering the potential to accelerate the discovery of therapeutic targets for muscle repair and regeneration.
Researchers from the Institute of Biomedical Engineering (BME) at the University of Toronto and the Translational Biology and Engineering Program in the Ted Rogers Centre for Heart Research have developed an ultrasound imaging protocol that promises to transform how congenital heart valve diseases are studied in mice. This new technique allows scientists to identify structural abnormalities in the aortic valve of juvenile mice as young as four weeks old, paving the way for more efficient, cost-effective, and humane research practices.
Initiated in 2015, the Joint Seed Program is an interdivisional research funding program designed to promote multi-disciplinary research and catalyze new innovative partnerships between researchers from the Faculty of Applied Science and Engineering and those from outside of Engineering. The recipients for this year will undertake unique and innovative research initiatives ranging from developing bioinoculant strategies to equitable healthcare and advanced imaging techniques.
A research team at UHN's Donald K. Johnson Eye Institute in collaboration with the Institute of Biomedical Engineering at the University of Toronto (U of T) has discovered that transplanted retinal cells can share essential materials with host cells in the lab, offering a promising avenue for delivering therapies directly to damaged areas of the eye.
One of the CBRF-funded programs is the Biomanufacturing Hub Network, an immersive talent development program based at the University of Toronto led by U of T University Professor Molly Shoichet (ChemE, BME) along with Darius Rackus, an assistant professor of chemistry and biology at Toronto Metropolitan University, and Gilbert Walker, a professor of chemistry at U of T.
Professor Omar F. Khan has been awarded the prestigious McCharles Prize for Early Career Research Distinction for his contributions to the fields of biomedical and immune engineering.
A study published in the Journal of Cell Science, led by Professor Penney Gilbert (BME) and Jo Nguyen at the University of Toronto, shed light on the impact of culture substrate stiffness and extracellular matrix (ECM) ligands on the contractility, proliferation, and various cellular processes of human myoblasts. The study aims to understand how these factors influence the regenerative activities of muscle stem cells and their progeny, with implications for aging and disease.
University of Toronto researchers have created a unique heart-on-a-chip model that is helping untangle the causes of COVID-19-induced heart inflammation and uncover strategies to reduce its impact.
New ways of growing human tissues outside the body, developed by Professor Alison McGuigan and her team, will help expand the ability of researchers to understand and control cell behaviour.
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