Posts Tagged: Cell & Tissue Engineering
Researchers at the University of Toronto and its partner hospitals have led the development of a heart-on-a-chip device to study the effects of a genetic mutation that causes dilated cardiomyopathy, a heart muscle disease that impairs blood flow throughout the body.
A team of researchers at the University of Toronto, led by Professor Craig Simmons, has introduced a novel method to engineer soft connective tissues with prescribed mechanical properties similar to those of native tissues. This finding, published in the journal Advanced Functional Materials, can propel the generation of more realistic tissues and organs for regenerative medicine in the future.
The Donnelly Centre for Cellular and Biomolecular Research is home to a new self-driving lab (SDL), borne out of a $200 million grant from the Canada First Research Excellence Fund to the Acceleration Consortium.
In a study published today, researchers from the University of Toronto have introduced an innovative biosensor, Apollo-NADP+, in living zebrafish embryos to track molecular metabolism. The study, featured in Science Advances, sheds light on the potential applications of this cutting-edge technology in understanding cellular processes and addresses a critical question in diabetes research.
U of T Engineering has partnered with CCRM, BioZone and the School of Continuing Studies on a new set of microcredentials that will help workers across Canada’s biomanufacturing industry to upgrade or strengthen their skills.
New innovations in the ways that human cells are grown in laboratories could help speed up the development of cellular therapy, a branch of regenerative medicine that targets diseases that are incurable today. According to Professor Julie Audet (BME), some of the most significant challenges to achieving this goal have to do with how the therapeutic cells are produced.
Researchers at the University of Toronto and the Ted Rogers Centre for Heart Research have identified a previously unknown mechanism that governs the movement of cardiac progenitors during heart development in fruit fly embryos. By using advanced imaging techniques, mathematical modelling and genetic and biophysical manipulations, Dr. Rodrigo Fernandez-Gonzalez and colleagues shed light on the formation of the early heart tube and provide insights into the cellular causes of congenital heart defects.
Researchers at the University of Toronto have made progress in understanding the intricate cellular processes involved in tissue development and repair. The findings, published in the journal Current Biology, shed light on the mechanisms underlying collective cell migration, a fundamental behavior that plays a crucial role in both normal embryo development and pathological conditions such as cancer metastasis.
A study from U of T Engineering researchers shows that mechanical deformation of medically implantable materials — such as bending or twisting — can have a big impact on the formation of potentially harmful biofilms.
University Professor Molly Shoichet has been elected a Fellow of the National Academy of Inventors (NAI).
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