Posts Tagged: Cell & Tissue Engineering
New innovations in the ways that human cells are grown in laboratories could help speed up the development of cellular therapy, a branch of regenerative medicine that targets diseases that are incurable today. According to Professor Julie Audet (BME), some of the most significant challenges to achieving this goal have to do with how the therapeutic cells are produced.
Researchers at the University of Toronto and the Ted Rogers Centre for Heart Research have identified a previously unknown mechanism that governs the movement of cardiac progenitors during heart development in fruit fly embryos. By using advanced imaging techniques, mathematical modelling and genetic and biophysical manipulations, Dr. Rodrigo Fernandez-Gonzalez and colleagues shed light on the formation of the early heart tube and provide insights into the cellular causes of congenital heart defects.
Researchers at the University of Toronto have made progress in understanding the intricate cellular processes involved in tissue development and repair. The findings, published in the journal Current Biology, shed light on the mechanisms underlying collective cell migration, a fundamental behavior that plays a crucial role in both normal embryo development and pathological conditions such as cancer metastasis.
A study from U of T Engineering researchers shows that mechanical deformation of medically implantable materials — such as bending or twisting — can have a big impact on the formation of potentially harmful biofilms.
University Professor Molly Shoichet has been elected a Fellow of the National Academy of Inventors (NAI).
The Donnelly Centre is swelling its ranks of leading researchers with two new faculty appointments.
A U of T Engineering research team has created a new platform that delivers multiple therapeutic proteins to the body, each at its own independently controlled rate. The innovation could help treat degenerative diseases such as age-related macular degeneration (AMD), the leading cause of vision loss for people over 50.
A team of U of T Engineering researchers, led by Professor Molly Shoichet (ChemE, BME, Donnelly), has designed a new way to grow cells in a laboratory that enables them to better emulate cancerous tumours.
U of T Engineering researchers have grown a small-scale model of a human left heart ventricle in the lab. The bioartificial tissue construct is made with living heart cells and beats strongly enough to pump fluid inside a bioreactor.
The Leap into the Future series looks at emerging areas or aspects of regenerative medicine.
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