Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, Canada

Dr. Budd A. Tucker, PhD University of Iowa Abstract: Inherited retinal degenerative disorders, ranging from relatively common conditions such as Stargardt disease to rare forms of retinitis pigmentosa, are extraordinarily genetically heterogeneous. To date more than 100 different genes and thousands of different disease-causing mutations have been identified. The unifying feature of these conditions is […]

Speaker Dr. Lonnie Shea, PhD University of Michigan Abstract Vaccines are the initial immunotherapy by providing a means to activate an immune response to specific antigens to protect against disease. This success has motivated the development of alternative immunotherapies for treating undesired immune responses, such as those found in autoimmune disease, allergy, organ transplantation, and […]

Speaker Dr. Johnna Temenoff, PhD Georgia Tech/Emory University Abstract After rotator cuff tendon tear, marked degeneration of the attached muscle is apparent clinically, with both fibrous and fatty infiltration of the tissue. Our laboratory is working on delivery strategies for biologics, including proteins and cells, that might slow or reverse this degeneration. In particular, our […]

Dr. Brian K. Shoichet, PhD University of California, San Francisco  https://utoronto.zoom.us/j/86086638773 Meeting ID: 860 8663 8773 Passcode: 484696 Structure-based docking can be used to screen compound libraries for novel ligands. Recently, docking libraries  have expanded from three million “in-stock” to over four billion make-on-demand (“tangible”) molecules. Docking these new libraries versus the dopamine, melatonin, and […]

Dr. Sanjiv Dhingra, PhD University of Manitoba Abstract: Donor derived allogeneic stem cells including mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) are being tested in animal studies and clinical trials for cardiac regeneration and repair. The outcome of initial studies was very encouraging and transplanted cells were safe in the recipient heart. However, […]

Dr. Laura Bracaglia, PhD Villanova University Polymer nanoparticles (NPs) can provide a safe and efficient delivery mechanism for therapy directly at specific tissues and cells, but achieving sufficient levels of NPs and therefore therapeutics in target tissues in humans has remained a barrier to the translation of this technology. The in vivo efficacy of polymeric […]

The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. Medicine by Design, in partnership with the McEwen Stem Cell Institute, is pleased to welcome Martin Fussenegger, PhD, Professor, Department of Biosystems Science and Engineering, ETH Zurich. The title of this talk […]

The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. Medicine by Design, in partnership with the McEwen Stem Cell Institute, is pleased to welcome Jacob (Yaqub) Hanna, PhD, Senior Scientist and Professor, Department of Molecular Genetics, Weizmann Institute of Science. The title […]