12 events found.
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, Canada
Events at this venue
Bioinspired Protein-based Cancer Immunotherapy (Dr. Yanpu He, UBC)
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaAbstract Immunotherapy has revolutionized the field of cancer treatment over the past two decades, though only a small fraction of patients treated will achieve complete remission. As such, new paradigms to overcome resistance to immunotherapies are urgently needed. My research seeks to tailor immunotherapies towards individual differences in immune systems and the inherent heterogeneity of […]
Using Patient Derived Induced Pluripotent Stem Cells to Model and Treat Inherited Retinal Disease
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaDr. Budd A. Tucker, PhD University of Iowa Abstract: Inherited retinal degenerative disorders, ranging from relatively common conditions such as Stargardt disease to rare forms of retinitis pigmentosa, are extraordinarily genetically heterogeneous. To date more than 100 different genes and thousands of different disease-causing mutations have been identified. The unifying feature of these conditions is […]
Immune Engineering: Detection and Treatment of Undesired Immune Responses – Dr. Johnna Temenoff
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaSpeaker Dr. Lonnie Shea, PhD University of Michigan Abstract Vaccines are the initial immunotherapy by providing a means to activate an immune response to specific antigens to protect against disease. This success has motivated the development of alternative immunotherapies for treating undesired immune responses, such as those found in autoimmune disease, allergy, organ transplantation, and […]
Mon Aug 21st – Carter Teal’s Public Seminar
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaCarter Teal will be having their public seminar on August 21st @ 1:00PM in the Red Room at the Donnley center.
Delivery of Biologics for Rotator Cuff Muscle Healing – Dr. Johnna Temenoff
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaSpeaker Dr. Johnna Temenoff, PhD Georgia Tech/Emory University Abstract After rotator cuff tendon tear, marked degeneration of the attached muscle is apparent clinically, with both fibrous and fatty infiltration of the tissue. Our laboratory is working on delivery strategies for biologics, including proteins and cells, that might slow or reverse this degeneration. In particular, our […]
Following the Rabbit into Chemical Space
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaDr. Brian K. Shoichet, PhD University of California, San Francisco https://utoronto.zoom.us/j/86086638773 Meeting ID: 860 8663 8773 Passcode: 484696 Structure-based docking can be used to screen compound libraries for novel ligands. Recently, docking libraries have expanded from three million “in-stock” to over four billion make-on-demand (“tangible”) molecules. Docking these new libraries versus the dopamine, melatonin, and […]
Carbon nanomaterials for cardiac regenerative medicine
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaDr. Sanjiv Dhingra, PhD University of Manitoba Abstract: Donor derived allogeneic stem cells including mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) are being tested in animal studies and clinical trials for cardiac regeneration and repair. The outcome of initial studies was very encouraging and transplanted cells were safe in the recipient heart. However, […]
Polymer Nanoparticle Design and Delivery Strategies to Resolve Vascular Inflammation
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaDr. Laura Bracaglia, PhD Villanova University Polymer nanoparticles (NPs) can provide a safe and efficient delivery mechanism for therapy directly at specific tissues and cells, but achieving sufficient levels of NPs and therefore therapeutics in target tissues in humans has remained a barrier to the translation of this technology. The in vivo efficacy of polymeric […]
BME Faculty Search Seminar – Tian He, Harvard University
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaIlluminating Bioelectricity in the Brain Dr. He Tian, Postdoctoral Associate, Harvard University The brain encodes and processes information through the dynamic membrane voltage of neurons. However, in vivo electrophysiology, i.e., the study of the membrane voltage of individual cells in live animals, has been a major challenge for neuroscience. In this seminar, I will present […]
Invited Academic Seminar Series – Cynthia Reinhart-King – The Intersection of Mechanobiology and Cellular Metabolism in Cancer (Hybrid Delivery)
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaSpeaker Cynthia Reinhart-King Cornelius Vanderbilt Professor of Engineering Professor of Biomedical Engineering Director of Graduate Studies in Biomedical Engineering Vanderbilt School of Engineering Abstract During solid tumor progression, cells undergo mechanical and metabolic changes that help to fuel metastasis. To move, cells must utilize ATP to fuel the the cellular contractility and forces that sustain […]
Global Speaker Series: Martin Fussenegger, PhD – ETH Zurich
Donnelly Centre for Cellular and Biomolecular Research, Red Room, 160 College Street, Toronto, Ontario, M5S 3E1, CanadaThe Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. Medicine by Design, in partnership with the McEwen Stem Cell Institute, is pleased to welcome Martin Fussenegger, PhD, Professor, Department of Biosystems Science and Engineering, ETH Zurich. The title of this talk […]