Research Interests

The McGuigan Lab develops engineered biomaterials to create artificial tissues that support drug discovery, guide treatment decisions, and potentially predict disease susceptibility. Unlike traditional 2D cell cultures, these 3D tissue models better replicate the complex cellular environments found in the human body, enabling more accurate studies of regeneration and disease. While promising, the use of artificial tissues to personalize therapies remains in early stages, as the signals driving individual cellular responses are still not fully understood.